Assembly of an SAP97-AKAP79-cAMP-dependent protein kinase scaffold at the type 1 PSD-95/DLG/ZO1 motif of the human beta(1)-adrenergic receptor generates a receptosome involved in receptor recycling and networking.
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SNX27 mediates PDZ-directed sorting from endosomes to the plasma membraneRole of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunityG protein-coupled receptors: what a difference a 'partner' makesEngineered protein connectivity to actin mimics PDZ-dependent recycling of G protein-coupled receptors but not its regulation by HrsSAP97 controls the trafficking and resensitization of the beta-1-adrenergic receptor through its PDZ2 and I3 domainsRegulation of GPCR activity, trafficking and localization by GPCR-interacting proteins.Decreased expression of A-kinase anchoring protein 150 in GT1 neurons decreases neuron excitability and frequency of intrinsic gonadotropin-releasing hormone pulses.Disruption of protein kinase A localization using a trans-activator of transcription (TAT)-conjugated A-kinase-anchoring peptide reduces cardiac function.Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice.A long lasting β1 adrenergic receptor stimulation of cAMP/protein kinase A (PKA) signal in cardiac myocytes.Sequential delivery of synaptic GluA1- and GluA4-containing AMPA receptors (AMPARs) by SAP97 anchored protein complexes in classical conditioningViagra for your synapses: Enhancement of hippocampal long-term potentiation by activation of beta-adrenergic receptors.Regulation of cardiac inward rectifier potassium current (I(K1)) by synapse-associated protein-97.Transcriptional activation of the anchoring protein SAP97 by heat shock factor (HSF)-1 stabilizes K(v) 1.5 channels in HL-1 cells.Carvedilol reverses cardiac insufficiency in AKAP5 knockout mice by normalizing the activities of calcineurin and CaMKII.The PDZ motif of the α1C subunit is not required for surface trafficking and adrenergic modulation of CaV1.2 channel in the heart.A Potential Role for a Genetic Variation of AKAP5 in Human Aggression and Anger ControlFirst introduction of highly pathogenic H5N1 avian influenza A viruses in wild and domestic birds in Denmark, Northern Europe.Hormonal signaling and signal pathway crosstalk in the control of myometrial calcium dynamics.Compartmentalization of beta-adrenergic signals in cardiomyocytes.Cell polarity proteins: common targets for tumorigenic human viruses.Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel.Role of ubiquitination in endocytic trafficking of G-protein-coupled receptors.A unique influenza A (H5N1) virus causing a focal poultry outbreak in 2007 in Manipur, India.Role of AKAP79/150 protein in β1-adrenergic receptor trafficking and signaling in mammalian cellsSorting of β1-adrenergic receptors is mediated by pathways that are either dependent on or independent of type I PDZ, protein kinase A (PKA), and SAP97.Three basic residues of intracellular loop 3 of the beta-1 adrenergic receptor are required for golgin-160-dependent trafficking.Regulation of β-adrenergic receptor function: an emphasis on receptor resensitization.G-protein coupled receptor resensitization-appreciating the balancing act of receptor function.Emerging role of the scaffolding protein Dlg1 in vesicle trafficking.Minireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling.G protein-coupled receptor 30 (GPR30) forms a plasma membrane complex with membrane-associated guanylate kinases (MAGUKs) and protein kinase A-anchoring protein 5 (AKAP5) that constitutively inhibits cAMP production.Barcoding of GPCR trafficking and signaling through the various trafficking roadmaps by compartmentalized signaling networks.Rab11a and its binding partners regulate the recycling of the ß1-adrenergic receptor.Role of SAP97 protein in the regulation of corticotropin-releasing factor receptor 1 endocytosis and extracellular signal-regulated kinase 1/2 signalingIdentification of novel transplantable GPCR recycling motif for drug discovery.The hydrophobic amino acid cluster at the cytoplasmic end of transmembrane helix III modulates the coupling of the β(1)-adrenergic receptor to G(s).Integration of GPCR Signaling and Sorting from Very Early Endosomes via Opposing APPL1 Mechanisms.Molecular pathways of oestrogen receptors and β-adrenergic receptors in cardiac cells: Recognition of their similarities, interactions and therapeutic value.AKAP79/150 interacts with the neuronal calcium-binding protein caldendrin.
P2860
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P2860
Assembly of an SAP97-AKAP79-cAMP-dependent protein kinase scaffold at the type 1 PSD-95/DLG/ZO1 motif of the human beta(1)-adrenergic receptor generates a receptosome involved in receptor recycling and networking.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Assembly of an SAP97-AKAP79-cA ...... ptor recycling and networking.
@en
type
label
Assembly of an SAP97-AKAP79-cA ...... ptor recycling and networking.
@en
prefLabel
Assembly of an SAP97-AKAP79-cA ...... ptor recycling and networking.
@en
P2093
P2860
P356
P1476
Assembly of an SAP97-AKAP79-cA ...... ptor recycling and networking.
@en
P2093
Anjaparavanda P Naren
Lidia A Gardner
Suleiman W Bahouth
P2860
P304
P356
10.1074/JBC.M608871200
P407
P577
2006-12-14T00:00:00Z