GIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activation - Wikidata - awgldk - TriplyDB

GIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activation

GIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activation

http://www.wikidata.org/entity/Q28201893

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G protein-coupled receptors participate in cytokinesis Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins Beta-2 adrenergic receptor mediated ERK activation is regulated by interaction with MAGI-3 How are the cellular functions of myosin VI regulated within the cell?GIPC binds to the human lutropin receptor (hLHR) through an unusual PDZ domain binding motif, and it regulates the sorting of the internalized human choriogonadotropin and the density of cell surface hLHR Inhibition of PKC phosphorylation of cTnI improves cardiac performance in vivo GLUT1CBP(TIP2/GIPC1) interactions with GLUT1 and myosin VI: evidence supporting an adapter function for GLUT1CBP AKAP79-mediated targeting of the cyclic AMP-dependent protein kinase to the beta1-adrenergic receptor promotes recycling and functional resensitization of the receptor Interactions of GIPC with dopamine D2, D3 but not D4 receptors define a novel mode of regulation of G protein-coupled receptors SAP97 controls the trafficking and resensitization of the beta-1-adrenergic receptor through its PDZ2 and I3 domains Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins.Functional proteomics, human genetics and cancer biology of GIPC family members A human monoclonal autoantibody to breast cancer identifies the PDZ domain containing protein GIPC1 as a novel breast cancer-associated antigen.The Drosophila GIPC homologue can modulate myosin based processes and planar cell polarity but is not essential for development.Minireview: Spatial Programming of G Protein-Coupled Receptor Activity: Decoding Signaling in Health and Disease Ligand-directed signalling at beta-adrenoceptors GIPC1 interacts with MyoGEF and promotes MDA-MB-231 breast cancer cell invasion.Diverse functions for the semaphorin receptor PlexinD1 in development and disease.Molecular characterization and ligand binding specificity of the PDZ domain-containing protein GIPC3 from Schistosoma japonicum.The PDZ protein GIPC regulates trafficking of the LPA1 receptor from APPL signaling endosomes and attenuates the cell's response to LPA.GIPC is recruited by APPL to peripheral TrkA endosomes and regulates TrkA trafficking and signaling Interactions between GIPC-APPL and GIPC-TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes.How regulators of G protein signaling achieve selective regulation.Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation Protein-protein interactions at the adrenergic receptors.Simvastatin alleviates cardiac fibrosis induced by infarction via up-regulation of TGF-β receptor III expression.Compartmentalization of beta-adrenergic signals in cardiomyocytes.Proteomic analysis of ERK1/2-mediated human sickle red blood cell membrane protein phosphorylation Dynamic mass redistribution reveals diverging importance of PDZ-ligands for G protein-coupled receptor pharmacodynamics A GIPC1-Palmitate Switch Modulates Dopamine Drd3 Receptor Trafficking and Signaling.A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes.Targeting GIPC/synectin in pancreatic cancer inhibits tumor growth.Spatially restricted G protein-coupled receptor activity via divergent endocytic compartments.GIPC recruits GAIP (RGS19) to attenuate dopamine D2 receptor signaling.A perspective on more effective GPCR-targeted drug discovery efforts.Minireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling.Na+/H+ exchanger regulatory factor-1 is involved in chemokine receptor homodimer CCR5 internalization and signal transduction but does not affect CXCR4 homodimer or CXCR4-CCR5 heterodimer.Barcoding of GPCR trafficking and signaling through the various trafficking roadmaps by compartmentalized signaling networks.Assembly of an SAP97-AKAP79-cAMP-dependent protein kinase scaffold at the type 1 PSD-95/DLG/ZO1 motif of the human beta(1)-adrenergic receptor generates a receptosome involved in receptor recycling and networking.TRP1 interacting PDZ-domain protein GIPC forms oligomers and is localized to intracellular vesicles in human melanocytes.

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GIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activation

http://www.wikidata.org/entity/Q28201893

description

2003 nî lūn-bûn

@nan

2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2003年の論文

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2003年論文

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2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

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name

GIPC interacts with the beta1- ...... ceptor-mediated ERK activation

@ast

GIPC interacts with the beta1- ...... ceptor-mediated ERK activation

@en

GIPC interacts with the beta1- ...... ceptor-mediated ERK activation

@nl

type

label

GIPC interacts with the beta1- ...... ceptor-mediated ERK activation

@ast

GIPC interacts with the beta1- ...... ceptor-mediated ERK activation

@en

GIPC interacts with the beta1- ...... ceptor-mediated ERK activation

@nl

prefLabel

GIPC interacts with the beta1- ...... ceptor-mediated ERK activation

@ast

GIPC interacts with the beta1- ...... ceptor-mediated ERK activation

@en

GIPC interacts with the beta1- ...... ceptor-mediated ERK activation

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

GIPC interacts with the beta1- ...... ceptor-mediated ERK activation

@en

P2093

Erin J Whalen

http://www.w3.org/2001/XMLSchema#string

Liaoyuan A Hu

http://www.w3.org/2001/XMLSchema#string

Robert J Lefkowitz

http://www.w3.org/2001/XMLSchema#string

Wei Chen

http://www.w3.org/2001/XMLSchema#string

P2860

GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP

beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2

beta 1-adrenergic receptor association with the synaptic scaffolding protein membrane-associated guanylate kinase inverted-2 (MAGI-2). Differential regulation of receptor internalization by MAGI-2 and PSD-95

A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling. Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC

The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange

The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins

GIPC and GAIP form a complex with TrkA: a putative link between G protein and receptor tyrosine kinase pathways

Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor

beta 1-adrenergic receptor association with PSD-95. Inhibition of receptor internalization and facilitation of beta 1-adrenergic receptor interaction with N-methyl-D-aspartate receptors

A PDZ protein regulates the distribution of the transmembrane semaphorin, M-SemF

P304

26295-26301

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scholarly article

P356

10.1074/JBC.M212352200

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P407

P433

28

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P478

278

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P50

Negin P. Martin

Richard T Premont

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2003-04-30T00:00:00Z

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P698

12724327

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