A ligand-based approach to identify quantitative structure-activity relationships for the androgen receptor.
about
Structural basis for antagonism and resistance of bicalutamide in prostate cancerSelective androgen receptor modulators in preclinical and clinical developmentDiscovery and therapeutic promise of selective androgen receptor modulatorsPharmacokinetics and pharmacodynamics of nonsteroidal androgen receptor ligandsChemistry and structural biology of androgen receptorCrystal Structure of the T877A Human Androgen Receptor Ligand-binding Domain Complexed to Cyproterone Acetate Provides Insight for Ligand-induced Conformational Changes and Structure-based Drug DesignEffect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulatorsComparison between steroid binding to membrane progesterone receptor alpha (mPRalpha) and to nuclear progesterone receptor: correlation with physicochemical properties assessed by comparative molecular field analysis and identification of mPRalpha-sDiscovery of the selective androgen receptor modulator MK-0773 using a rational development strategy based on differential transcriptional requirements for androgenic anabolism versus reproductive physiologyThe selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial.Nonsteroidal selective androgen receptor modulators enhance female sexual motivation.Recent advances in ligand-based drug design: relevance and utility of the conformationally sampled pharmacophore approach.Structural basis for computational screening of non-steroidal androgen receptor ligands.Pharmacophore-based discovery of ligands for drug transporters.Antiandrogenic properties of parabens and other phenolic containing small molecules in personal care products.Regulation of androgen receptor signaling in prostate cancer.Structural basis for accommodation of nonsteroidal ligands in the androgen receptorAdvances in male hormone substitution therapy.In vitro and in vivo structure-activity relationships of novel androgen receptor ligands with multiple substituents in the B-ringSynthesis of irreversibly binding bicalutamide analogs for imaging studiesSynthesis of oxazolidinedione derived bicalutamide analogs.Arylisothiocyanato selective androgen receptor modulators (SARMs) for prostate cancer.Ligand-independent androgen receptor activity is activation function-2-independent and resistant to antiandrogens in androgen refractory prostate cancer cells.Emerging drugs: mechanism of action, mass spectrometry and doping control analysis.Enzalutamide and blocking androgen receptor in advanced prostate cancer: lessons learnt from the history of drug development of antiandrogens.LASSO-ing Potential Nuclear Receptor Agonists and Antagonists: A New Computational Method for Database Screening
P2860
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P2860
A ligand-based approach to identify quantitative structure-activity relationships for the androgen receptor.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
A ligand-based approach to ide ...... ips for the androgen receptor.
@en
type
label
A ligand-based approach to ide ...... ips for the androgen receptor.
@en
prefLabel
A ligand-based approach to ide ...... ips for the androgen receptor.
@en
P2093
P2860
P356
P1476
A ligand-based approach to ide ...... ips for the androgen receptor.
@en
P2093
Casey E Bohl
Cheng Chang
Duane D Miller
James T Dalton
Jiyun Chen
Michael L Mohler
Peter W Swaan
P2860
P304
P356
10.1021/JM0499007
P407
P577
2004-07-01T00:00:00Z