Homology modeling using multiple molecular dynamics simulations and docking studies of the human androgen receptor ligand binding domain bound to testosterone and nonsteroidal ligands.
about
Structure-activity relationship for thiohydantoin androgen receptor antagonists for castration-resistant prostate cancer (CRPC)Selective androgen receptor modulators in preclinical and clinical developmentDiscovery and therapeutic promise of selective androgen receptor modulatorsChemistry and structural biology of androgen receptorInteraction of organophosphate pesticides and related compounds with the androgen receptorCrystal Structure of the T877A Human Androgen Receptor Ligand-binding Domain Complexed to Cyproterone Acetate Provides Insight for Ligand-induced Conformational Changes and Structure-based Drug DesignVirtual ligand screening against comparative protein structure models.Disturbance of DNA conformation by the binding of testosterone-based platinum drugs via groove-face and intercalative interactions: a molecular dynamics simulation study.Molecular docking screens using comparative models of proteinsA critical role of helix 3-helix 5 interaction in steroid hormone receptor functionThe androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity.Structure-based systems biology for analyzing off-target bindingInteractions of androgens, green tea catechins and the antiandrogen flutamide with the external glucose-binding site of the human erythrocyte glucose transporter GLUT1.Similarities and Distinctions in Actions of Surface-Directed and Classic Androgen Receptor Antagonists.Structural basis for accommodation of nonsteroidal ligands in the androgen receptorSynthesis of irreversibly binding bicalutamide analogs for imaging studiesSynthesis of oxazolidinedione derived bicalutamide analogs.Arylisothiocyanato selective androgen receptor modulators (SARMs) for prostate cancer.Helix 3-helix 5 interactions in steroid hormone receptor functionSubfertile female androgen receptor knockout mice exhibit defects in neuroendocrine signaling, intraovarian function, and uterine development but not uterine function.Effect-based assessment of persistent organic pollutant and pesticide dumpsite using mammalian CALUX reporter cell lines.Inhibition of the androgen receptor by mineralocorticoids at levels physiologically achieved in serum in patients treated with abiraterone acetate.Androgen receptor variation affects prostate cancer progression and drug resistance.A ligand-based approach to identify quantitative structure-activity relationships for the androgen receptor.Efficacy of Immediate Switching from Bicalutamide to Flutamide as Second-Line Combined Androgen Blockade.Broadened ligand responsiveness of androgen receptor mutants obtained by random amino acid substitution of H874 and mutation hot spot T877 in prostate cancer.The binding mode of progesterone to its receptor deduced from molecular dynamics simulations.Decision trees versus support vector machine for classification of androgen receptor ligands.
P2860
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P2860
Homology modeling using multiple molecular dynamics simulations and docking studies of the human androgen receptor ligand binding domain bound to testosterone and nonsteroidal ligands.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Homology modeling using multip ...... rone and nonsteroidal ligands.
@en
Homology modeling using multip ...... rone and nonsteroidal ligands.
@nl
type
label
Homology modeling using multip ...... rone and nonsteroidal ligands.
@en
Homology modeling using multip ...... rone and nonsteroidal ligands.
@nl
prefLabel
Homology modeling using multip ...... rone and nonsteroidal ligands.
@en
Homology modeling using multip ...... rone and nonsteroidal ligands.
@nl
P2093
P356
P1476
Homology modeling using multip ...... erone and nonsteroidal ligands
@en
P2093
A Mukherjee
C A Marhefka
D D Miller
L Kirkovsky
T C Bishop
P304
P356
10.1021/JM0005353
P407
P577
2001-05-01T00:00:00Z