Neurochemical changes in Huntington R6/2 mouse striatum detected by in vivo 1H NMR spectroscopy.
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Early alterations of brain cellular energy homeostasis in Huntington disease modelsMetabolic disturbances in diseases with neurological involvementThe Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver DiseasesHdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid AccumulationHomeostatic adaptations in brain energy metabolism in mouse models of Huntington diseaseR6/2 Huntington's disease mice develop early and progressive abnormal brain metabolism and seizures.Impaired brain creatine kinase activity in Huntington's disease.The expanded CAG repeat in the huntingtin gene as target for therapeutic RNA modulation throughout the HD mouse brain.Probing the metabolic aberrations underlying mutant huntingtin toxicity in yeast and assessing their degree of preservation in humans and mice.Initial in vivo rodent sodium and proton MR imaging at 21.1 T.Magnetic resonance spectroscopy of regional brain metabolite markers in FALS mice and the effects of dietary creatine supplementation.Does closure of acid-sensing ion channels reduce ischemia/reperfusion injury in the rat brain?Neurochemical alterations in spinocerebellar ataxia type 1 and their correlations with clinical status.Acamprosate reduces ethanol drinking behaviors and alters the metabolite profile in mice lacking ENT1Acidosis, acid-sensing ion channels, and neuronal cell death.Dysregulation of system xc(-) expression induced by mutant huntingtin in a striatal neuronal cell line and in R6/2 micePreclinical (1)H-MRS neurochemical profiling in neurological and psychiatric disorders.ROC-supervised principal component analysis in connection with the diagnosis of diseasesApplication of clustering analyses to the diagnosis of Huntington disease in mice and other diseases with well-defined group boundariesCuprizone-induced demyelination and demyelination-associated inflammation result in different proton magnetic resonance metabolite spectra.In vivo monitoring of recovery from neurodegeneration in conditional transgenic SCA1 miceRegion-specific changes in ascorbate concentration during rat brain development quantified by in vivo (1)H NMR spectroscopy.Cortical metabolites as biomarkers in the R6/2 model of Huntington's disease.Up-regulation of GLT1 reverses the deficit in cortically evoked striatal ascorbate efflux in the R6/2 mouse model of Huntington's disease.Cerebral metabolite abnormalities in human immunodeficiency virus are associated with cortical and subcortical volumes.Proton MR spectroscopy-detectable major neurotransmitters of the brain: biology and possible clinical applications.Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.Modeling kinetics of subcellular disposition of chemicals.Measurement of Total Antioxidant Capacity in Sub-μL Blood Samples Using Craft Paper-based Analytical Devices.Neurochemical changes in the rat prefrontal cortex following acute phencyclidine treatment: an in vivo localized (1)H MRS study.Corticostriatal dysfunction underlies diminished striatal ascorbate release in the R6/2 mouse model of Huntington's disease.Comparison of analytical mathematical approaches for identifying key nuclear magnetic resonance spectroscopy biomarkers in the diagnosis and assessment of clinical change of diseases.Energy deficit in Huntington disease: why it matters.Corticostriatal dysfunction and glutamate transporter 1 (GLT1) in Huntington's disease: interactions between neurons and astrocytes.Huntington's Disease: Pathogenic Mechanisms and Therapeutic Targets.A longitudinal study of magnetic resonance spectroscopy Huntington's disease biomarkers.Similar Progression of Morphological and Metabolic Phenotype in R6/2 Mice with Different CAG Repeats Revealed by In Vivo Magnetic Resonance Imaging and Spectroscopy.Dysregulation of corticostriatal ascorbate release and glutamate uptake in transgenic models of Huntington's disease.Assessment of brain metabolite correlates of adeno-associated virus-mediated over-expression of human alpha-synuclein in cortical neurons by in vivo (1) H-MR spectroscopy at 9.4 T.Brain neurochemical and hemodynamic findings in the NY1DD mouse model of mild sickle cell disease.
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P2860
Neurochemical changes in Huntington R6/2 mouse striatum detected by in vivo 1H NMR spectroscopy.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Neurochemical changes in Hunti ...... y in vivo 1H NMR spectroscopy.
@en
type
label
Neurochemical changes in Hunti ...... y in vivo 1H NMR spectroscopy.
@en
prefLabel
Neurochemical changes in Hunti ...... y in vivo 1H NMR spectroscopy.
@en
P2093
P2860
P1476
Neurochemical changes in Hunti ...... y in vivo 1H NMR spectroscopy.
@en
P2093
C Dirk Keene
Janet M Dubinsky
Walter C Low
P2860
P304
P356
10.1111/J.1471-4159.2006.04323.X
P407
P577
2007-01-08T00:00:00Z