about
Possible involvement of self-defense mechanisms in the preferential vulnerability of the striatum in Huntington's diseasedAtaxin-2 mediates expanded Ataxin-1-induced neurodegeneration in a Drosophila model of SCA1Altered hypothalamic protein expression in a rat model of Huntington's diseaseThe DISC locus in psychiatric illnessNeurodegenerative disease and adult neurogenesisScalable production in human cells and biochemical characterization of full-length normal and mutant huntingtinAblation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis.N-terminal Huntingtin Knock-In Mice: Implications of Removing the N-terminal Region of Huntingtin for Therapy.Localization of BDNF mRNA with the Huntington's disease protein in rat brain.Interaction of huntingtin fragments with brain membranes--clues to early dysfunction in Huntington's disease.Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntington's disease.Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtinHigh-Throughput Multiplexed Quantitation of Protein Aggregation and Cytotoxicity in a Huntington's Disease Model.Huntington disease (chorea) in the middle East.Cognitive and autonomic dysfunction in presymptomatic and early Huntington's disease.Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease.Direct reprogramming of Huntington's disease patient fibroblasts into neuron-like cells leads to abnormal neurite outgrowth, increased cell death, and aggregate formationQuantitative 7T phase imaging in premanifest Huntington disease.Transgenic mouse model expressing the caspase 6 fragment of mutant huntingtin.The group 2 metabotropic glutamate receptor agonist LY379268 rescues neuronal, neurochemical and motor abnormalities in R6/2 Huntington's disease miceSuppression of neurodegeneration and increased neurotransmission caused by expanded full-length huntingtin accumulating in the cytoplasmHuntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies.Age-Dependent Resistance to Excitotoxicity in Htt CAG140 Mice and the Effect of Strain Background.miR-196a ameliorates phenotypes of Huntington disease in cell, transgenic mouse, and induced pluripotent stem cell models.Sirtuin deacetylases as therapeutic targets in the nervous systemLarge animal models of neurological disorders for gene therapy.Axonal transport defects in neurodegenerative diseases.Use of genetically modified mesenchymal stem cells to treat neurodegenerative diseases.Adult neurogenesis in neurodegenerative diseases.The Differential Profiling of Ubiquitin-Proteasome and Autophagy Systems in Different Tissues before the Onset of Huntington's Disease Models.Huntington's Disease and Mitochondria.Neurochemical changes in Huntington R6/2 mouse striatum detected by in vivo 1H NMR spectroscopy.Genotype-dependent priming to self- and xeno-cannibalism in heterozygous and homozygous lymphoblasts from patients with Huntington's disease.Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease.Calretinin interacts with huntingtin and reduces mutant huntingtin-caused cytotoxicity.Genotype-, aging-dependent abnormal caspase activity in Huntington disease blood cells.The Benefits of Exercise on Structural and Functional Plasticity in the Rodent Hippocampus of Different Disease Models.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Huntingtin and its role in neuronal degeneration
@ast
Huntingtin and its role in neuronal degeneration
@en
Huntingtin and its role in neuronal degeneration
@nl
type
label
Huntingtin and its role in neuronal degeneration
@ast
Huntingtin and its role in neuronal degeneration
@en
Huntingtin and its role in neuronal degeneration
@nl
prefLabel
Huntingtin and its role in neuronal degeneration
@ast
Huntingtin and its role in neuronal degeneration
@en
Huntingtin and its role in neuronal degeneration
@nl
P2860
P356
P1433
P1476
Huntingtin and its role in neuronal degeneration
@en
P2093
Shi-Hua Li
Xiao-Jiang Li
P2860
P304
P356
10.1177/1073858404266777
P407
P577
2004-10-01T00:00:00Z