about
Vigorous response of human innate functioning IgM memory B cells upon infection by Neisseria gonorrhoeaeDevelopment and Characterization of Potent Cyclic Acyldepsipeptide Analogues with Increased Antimicrobial ActivityGlobal analysis of neutrophil responses to Neisseria gonorrhoeae reveals a self-propagating inflammatory programThe bacterial virulence factor InlC perturbs apical cell junctions and promotes cell-to-cell spread of Listeria.Characterization of the Moraxella catarrhalis opa-like protein, OlpA, reveals a phylogenetically conserved family of outer membrane proteins.Opa binding to cellular CD66 receptors mediates the transcellular traversal of Neisseria gonorrhoeae across polarized T84 epithelial cell monolayers.Adherent-invasive Escherichia coli, strain LF82 disrupts apical junctional complexes in polarized epitheliaExposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocationDifferential response of primary and immortalized CD4+ T cells to Neisseria gonorrhoeae-induced cytokines determines the effect on HIV-1 replication.Host cell invasion by pathogenic Neisseriae.The structural basis of CEACAM-receptor targeting by neisserial Opa proteins.Phosphatidylinositol 3-kinases in carcinoembryonic antigen-related cellular adhesion molecule-mediated internalization of Neisseria gonorrhoeae.Immunoreceptor tyrosine-based activation motif phosphorylation during engulfment of Neisseria gonorrhoeae by the neutrophil-restricted CEACAM3 (CD66d) receptor.Total synthesis and antibacterial testing of the A54556 cyclic acyldepsipeptides isolated from Streptomyces hawaiiensis.Association of Neisseria gonorrhoeae Opa(CEA) with dendritic cells suppresses their ability to elicit an HIV-1-specific T cell memory responseSterilizing immunity elicited by Neisseria meningitidis carriage shows broader protection than predicted by serum antibody cross-reactivity in CEACAM1-humanized mice.In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa.A native outer membrane vesicle vaccine confers protection against meningococcal colonization in human CEACAM1 transgenic mice.Selection for a CEACAM receptor-specific binding phenotype during Neisseria gonorrhoeae infection of the human genital tract.Characterization of transferrin binding proteins 1 and 2 in invasive type b and nontypeable strains of Haemophilus influenzae.Neisserial Opa proteins: impact on colonization, dissemination and immunity.Neisseria gonorrhoeae selectively suppresses the development of Th1 and Th2 cells, and enhances Th17 cell responses, through TGF-β-dependent mechanisms.The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD.Heptose Sounds the Alarm: Innate Sensing of a Bacterial Sugar Stimulates ImmunityInvasive potential of nonencapsulated disease isolates of Neisseria meningitidis.Neisseria gonorrhoeae-derived heptose elicits an innate immune response and drives HIV-1 expressionThe reproductive cycle is a pathogenic determinant during gonococcal pelvic inflammatory disease in mice.Summary and Recommendations from the National Institute of Allergy and Infectious Diseases (NIAID) Workshop "Gonorrhea Vaccines: the Way Forward".Inside-out signaling promotes dynamic changes in the carcinoembryonic antigen-related cellular adhesion molecule 1 (CEACAM1) oligomeric state to control its cell adhesion properties.Opa proteins and CEACAMs: pathways of immune engagement for pathogenic Neisseria.The global roadmap for advancing development of vaccines against sexually transmitted infections: Update and next steps.Murine Plasmodium chabaudi malaria increases mucosal immune activation and the expression of putative HIV susceptibility markers in the gut and genital mucosae.Adherent-invasive Escherichia coli blocks interferon-γ-induced signal transducer and activator of transcription (STAT)-1 in human intestinal epithelial cells.Defining the roles of human carcinoembryonic antigen-related cellular adhesion molecules during neutrophil responses to Neisseria gonorrhoeae.Carcinoembryonic antigen family receptor specificity of Neisseria meningitidis Opa variants influences adherence to and invasion of proinflammatory cytokine-activated endothelial cells.Adherent-invasive Escherichia coli target the epithelial barrier.Bcl10 synergistically links CEACAM3 and TLR-dependent inflammatory signalling.TIFA Signaling in Gastric Epithelial Cells Initiates the cag Type 4 Secretion System-Dependent Innate Immune Response to Helicobacter pylori Infection.Arrested maturation of Neisseria-containing phagosomes in the absence of the lysosome-associated membrane proteins, LAMP-1 and LAMP-2.Innate Recognition of Intracellular Bacterial Growth Is Driven by the TIFA-Dependent Cytosolic Surveillance Pathway.
P50
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P50
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Scott D Gray-Owen
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P106
P1153
6701538487
P21
P2798
P31
P496
0000-0002-1477-3616