PAX6 suppresses the invasiveness of glioblastoma cells and the expression of the matrix metalloproteinase-2 gene.
about
Gliomas induce and exploit microglial MT1-MMP expression for tumor expansionIncreased nucleotide polymorphic changes in the 5'-untranslated region of delta-catenin (CTNND2) gene in prostate cancerPAX6 suppression of glioma angiogenesis and the expression of vascular endothelial growth factor ARegulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma.Pax6 expression is sufficient to induce a neurogenic fate in glial progenitors of the neonatal subventricular zonePax6 represses androgen receptor-mediated transactivation by inhibiting recruitment of the coactivator SPBP.PAX6 downregulates miR-124 expression to promote cell migration during embryonic stem cell differentiation.Pax6 directly down-regulates Pcsk1n expression thereby regulating PC1/3 dependent proinsulin processing.Ellagic Acid, the Active Compound of Phyllanthus urinaria, Exerts In Vivo Anti-Angiogenic Effect and Inhibits MMP-2 ActivityTumor-specific chromosome mis-segregation controls cancer plasticity by maintaining tumor heterogeneityPax6 regulates the expression of Dkk3 in murine and human cell lines, and altered responses to Wnt signaling are shown in FlpIn-3T3 cells stably expressing either the Pax6 or the Pax6(5a) isoform.EFEMP1 suppresses malignant glioma growth and exerts its action within the tumor extracellular compartment.PAX Genes in Cancer; Friends or Foes?Pax genes in embryogenesis and oncogenesis.MicroRNA-10b pleiotropically regulates invasion, angiogenicity and apoptosis of tumor cells resembling mesenchymal subtype of glioblastoma multiformeCell context-dependent dual effects of EFEMP1 stabilizes subpopulation equilibrium in responding to changes of in vivo growth environmentTumor suppressor PAX6 functions as androgen receptor co-repressor to inhibit prostate cancer growthWeaponizing human EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1) for 21st century cancer therapeutics.PAX6 is expressed in pancreatic cancer and actively participates in cancer progression through activation of the MET tyrosine kinase receptor gene.Downregulation of PAX6 by shRNA inhibits proliferation and cell cycle progression of human non-small cell lung cancer cell lines.Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth.Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells.The sonic hedgehog-GLI1 signaling pathway in brain tumor development.The shaping of invasive glioma phenotype by the ubiquitin-proteasome system.Role of miR-223/paired box 6 signaling in temozolomide chemoresistance in glioblastoma multiforme cells.Clinical Value and Prospective Pathway Signaling of MicroRNA-375 in Lung Adenocarcinoma: A Study Based on the Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO) and Bioinformatics AnalysisIrradiation of primary human gliomas triggers dynamic and aggressive survival responses involving microvesicle signaling.Characterization of matrix metalloproteinase-2 and -9, ADAM-10 and N-cadherin expression in human glioblastoma multiforme.MiR-365b-3p, down-regulated in retinoblastoma, regulates cell cycle progression and apoptosis of human retinoblastoma cells by targeting PAX6.The immunological function of GABAergic system.Dlxin-1, a member of MAGE family, inhibits cell proliferation, invasion and tumorigenicity of glioma stem cells.Isoform- and dose-sensitive feedback interactions between paired box 6 gene and delta-catenin in cell differentiation and death.MicroRNA-375 targets PAX6 and inhibits the viability, migration and invasion of human breast cancer MCF-7 cellsTracking Functional Tumor Cell Subpopulations of Malignant Glioma by Phasor Fluorescence Lifetime Imaging Microscopy of NADH.The role of EGFR double minutes in modulating the response of malignant gliomas to radiotherapy.Human fibulin-3 protein variant expresses anti-cancer effects in the malignant glioma extracellular compartment in intracranial xenograft models.MiR-338-5p Promotes Glioma Cell Invasion by Regulating TSHZ3 and MMP2.TIPE1 suppresses invasion and migration through down-regulating Wnt/β-catenin pathway in gastric cancer.Generation of a PAX6 knockout glioblastoma cell line with changes in cell cycle distribution and sensitivity to oxidative stress.Microglia/Astrocytes-Glioblastoma Crosstalk: Crucial Molecular Mechanisms and Microenvironmental Factors
P2860
Q30489174-A6FEC903-30DE-41AE-9056-47C00A1AD817Q33382065-0D2593B5-E693-4CA3-BBE7-114AB00AEAB8Q33599207-41A5BAB1-6743-4AAC-A1D5-69A548C01A22Q33741183-B7D357D6-0CC3-4AE8-BBC8-9C28B0E270C0Q33940644-54374031-727E-45B7-926C-E7FDA178E41AQ34026199-2CDC55E7-35FC-4861-AE45-265DC20A08B8Q34231649-27294507-7576-4249-8C2F-8814297C61D4Q34442538-018ACBBD-8652-4A48-B988-691657325145Q34983870-46BBCB5F-2245-4A9A-A32D-B2F520E07E71Q35055173-E3F920BB-250D-4641-A4B3-B1BC06D27A8AQ35207631-7FF5F594-6EC6-400B-9907-12138B1A00BAQ35478122-4AE05E07-40EC-4577-A12D-D206B705DAF5Q35714437-13CFD086-5EB4-43EB-8B07-1DD3C08D710AQ35886629-CA53653C-988A-405A-AF96-719534A5F63BQ36347204-5B068109-6E9A-4EDA-B31C-D196E13452E9Q36544417-3A440266-C292-4DCF-921C-F5860C8832CBQ37059542-6583B24C-268F-404C-ADE1-8CB4FB723C8DQ37298184-2AC3187F-888B-4B17-BAD2-0D71EB8A6090Q37448101-31D0FA07-F0F9-42CA-97F8-D15F9C02C697Q37484345-A803FA84-2E65-435C-B951-FC0C004D80E1Q37658825-F0E2EFF7-AE6E-4598-8950-CD5E248852F9Q37690963-9AE3A750-E7FB-49F4-8A5C-D01A00A202F0Q38044769-E532AFCB-9F0E-4C7A-A547-59D12719FF1FQ38134142-A824FFDE-9249-473D-8C4F-7CCDFD1C119DQ38289553-5D4AE7DF-E5CB-4A3F-A4CD-1ADCDDA40DD3Q38433308-AB0C178C-B97A-48C3-880B-4B0575D36095Q38817114-4628CCD0-8E62-4F4E-A2D2-1263547C0D63Q38878322-D41BC927-C1DF-4DC9-8573-DBACDC1F9801Q39154132-9AF35FC8-F948-42DA-883E-E9CCDDDFEEA1Q39242855-A8B71E21-BBC1-495C-AB2C-C38848D0C3F8Q39627253-771A9CDD-4A4D-4EF7-9736-3F37565F129DQ39751952-44B6629D-29C3-455B-B20A-E8213775E158Q41113404-DE02E3C9-EDDB-49F0-BC9E-25796271E585Q45938874-39AE4478-DF86-47CA-B1A2-0B4EE7EEC288Q46720726-6D782128-FC10-4E3E-A234-0EA8DFFD9902Q47128907-69B9AD10-18FC-4D5E-9FD8-E064E25235F7Q47986918-BF10BF6D-672F-4443-ACF2-C7F3C984689AQ48217787-B0D0BE22-0479-486C-A374-C22E7504EBD0Q52715022-674D25E3-4221-4A16-BFD5-E8D192F29CA8Q58801546-E39A920A-7190-41ED-AA0C-1D925F28A83B
P2860
PAX6 suppresses the invasiveness of glioblastoma cells and the expression of the matrix metalloproteinase-2 gene.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
PAX6 suppresses the invasivene ...... trix metalloproteinase-2 gene.
@en
type
label
PAX6 suppresses the invasivene ...... trix metalloproteinase-2 gene.
@en
prefLabel
PAX6 suppresses the invasivene ...... trix metalloproteinase-2 gene.
@en
P2093
P1433
P1476
PAX6 suppresses the invasivene ...... trix metalloproteinase-2 gene.
@en
P2093
Debra A Mayes
Eric Siegel
Kishori Panda
W K Alfred Yung
Xiaosong Wu
Yi-Hong Zhou
Yuanjie Hu
P304
P356
10.1158/0008-5472.CAN-05-3877
P407
P577
2006-10-01T00:00:00Z