EFEMP1 suppresses malignant glioma growth and exerts its action within the tumor extracellular compartment. - Wikidata - awgldk - TriplyDB

EFEMP1 suppresses malignant glioma growth and exerts its action within the tumor extracellular compartment.

EFEMP1 suppresses malignant glioma growth and exerts its action within the tumor extracellular compartment.

http://www.wikidata.org/entity/Q35478122

about

Fibulin-3 as a blood and effusion biomarker for pleural mesothelioma.Molecular mechanisms of tissue inhibitor of metalloproteinase 2 in the tumor microenvironment TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells A simple knowledge-based mining method for exploring hidden key molecules in a human biomolecular network.Fibulin-4 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition via the PI3K/Akt/mTOR pathway.Impact of interaction between the G870A and EFEMP1 gene polymorphism on glioma risk in Chinese Han population.Novel paracrine modulation of Notch-DLL4 signaling by fibulin-3 promotes angiogenesis in high-grade gliomas.Anti-EGFR function of EFEMP1 in glioma cells and patient prognosis.Overexpression of EFEMP1 correlates with tumor progression and poor prognosis in human ovarian carcinoma Tumor-specific chromosome mis-segregation controls cancer plasticity by maintaining tumor heterogeneity Fibulin-4 is associated with tumor progression and a poor prognosis in ovarian carcinomas Mitochondrial DNA variants can mediate methylation status of inflammation, angiogenesis and signaling genes.EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway.Fibulin-3 levels in malignant pleural mesothelioma are associated with prognosis but not diagnosis.Cell context-dependent dual effects of EFEMP1 stabilizes subpopulation equilibrium in responding to changes of in vivo growth environment Epidermal growth factor-containing fibulin-like extracellular matrix protein 1 expression and regulation in uterine leiomyoma.Decrease of fibulin-3 in hepatocellular carcinoma indicates poor prognosis.Weaponizing human EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1) for 21st century cancer therapeutics.Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration.Fibulin-3 promotes glioma growth and resistance through a novel paracrine regulation of Notch signaling.EFEMP1 promotes ovarian cancer cell growth, invasion and metastasis via activated the AKT pathway.Fibulin-4 is associated with prognosis of endometrial cancer patients and inhibits cancer cell invasion and metastasis via Wnt/β-catenin signaling pathway.Interleukin-1-induced changes in the glioblastoma secretome suggest its role in tumor progression.Fibulin-3-mediated inhibition of epithelial-to-mesenchymal transition and self-renewal of ALDH+ lung cancer stem cells through IGF1R signaling.Plasma Fibulin-3 as a Potential Biomarker for Patients with Asbestos-Related Diseases in the Han Population.The associations between common SNPs of EFEMP1 gene and glioma risk in Chinese population.Human fibulin-3 protein variant expresses anti-cancer effects in the malignant glioma extracellular compartment in intracranial xenograft models.Deconvolution of Human Brain Cell Type Transcriptomes Unraveled Microglia-Specific Potential Biomarkers.

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EFEMP1 suppresses malignant glioma growth and exerts its action within the tumor extracellular compartment.

http://www.wikidata.org/entity/Q35478122

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

@zh-cn

2011年学术文章

@zh-hans

2011年学术文章

@zh-my

2011年学术文章

@zh-sg

2011年學術文章

@yue

name

EFEMP1 suppresses malignant gl ...... mor extracellular compartment.

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EFEMP1 suppresses malignant gl ...... mor extracellular compartment.

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type

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EFEMP1 suppresses malignant gl ...... mor extracellular compartment.

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EFEMP1 suppresses malignant gl ...... mor extracellular compartment.

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1476-4598-10-123

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Molecular Cancer

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EFEMP1 suppresses malignant gl ...... mor extracellular compartment.

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Abhishek Chaturbedi

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Daniel I Ro

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Eric Siegel

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Jodi Nelson

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Kenneth R Hess

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Liping Yu

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Mark E Linskey

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Mark Hamamura

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Marlon S Mathews

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Nelson Hsu

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P2860

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Direct control of the Forkhead transcription factor AFX by protein kinase B

EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors

Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation

Fibulin-3 is uniquely upregulated in malignant gliomas and promotes tumor cell motility and invasion

Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase

Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis

PAX6 suppression of glioma angiogenesis and the expression of vascular endothelial growth factor A

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Bruce J. Tromberg

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2011-09-28T00:00:00Z

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51678323

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