Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.
about
Targeting caspases in cancer therapeuticsA novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activityNon-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors: an integrated strategy for the development of new antiangiogenic compounds.Survivin, a molecular target for therapeutic interventions in squamous cell carcinoma.Targeting the 90 kDa heat shock protein improves photodynamic therapy.Generation of a novel transgenic mouse model for bioluminescent monitoring of survivin gene activity in vivo at various pathophysiological processes: survivin expression overlaps with stem cell markersTargeting Hsp90 with small molecule inhibitors induces the over-expression of the anti-apoptotic molecule, survivin, in human A549, HONE-1 and HT-29 cancer cells.Prostate cancer regulatory networksUtilization of the cellular stress response to sensitize cancer cells to TRAIL-mediated apoptosis.Heat shock protein 90 regulates the expression of Wilms tumor 1 protein in myeloid leukemiasStructural basis for depletion of heat shock protein 90 client proteins by deguelin.Targeting survivin in cancer: novel drug development approaches.Apoptosis repressor with caspase recruitment domain modulates second mitochondrial-derived activator of caspases mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemiaBroad targeting of resistance to apoptosis in cancer.Understanding ligand-based modulation of the Hsp90 molecular chaperone dynamics at atomic resolution.Inhibitors of the heat shock response: biology and pharmacology.New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential.Impact of heat-shock protein 90 on cancer metastasisCompartmentalized cancer drug discovery targeting mitochondrial Hsp90 chaperones.Survivin: a target from brain cancer to neurodegenerative disease.Targeting survivin in cancer: patent review.Clinico-pathologic relevance of Survivin splice variant expression in cancerβ-Lapachone Induces NAD(P)H:Quinone Oxidoreductase-1- and Oxidative Stress-Dependent Heat Shock Protein 90 Cleavage and Inhibits Tumor Growth and Angiogenesis.The apoptotic effect and associated signalling of HSP90 inhibitor 17-DMAG in hepatocellular carcinoma cells.A bombesin-shepherdin radioconjugate designed for combined extra- and intracellular targeting.The Interface between BCR-ABL-Dependent and -Independent Resistance Signaling Pathways in Chronic Myeloid Leukemia.Mitochondrial heat shock protein-90 modulates vascular smooth muscle cell survival and the vascular injury response in vivo.Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent.Inhibitor of Apoptosis Proteins: Promising Targets for Cancer Therapy.
P2860
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P2860
Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.
@en
type
label
Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.
@en
prefLabel
Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.
@en
P2093
P50
P356
P1476
Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors
@en
P2093
Bing Z Carter
Christopher M Raskett
Dario C Altieri
David S Garlick
Janet Plescia
Michael Andreeff
Philip A Lowry
P304
P356
10.1093/JNCI/DJJ300
P407
P577
2006-08-01T00:00:00Z