Mutant actins that stabilise F-actin use distinct mechanisms to activate the SRF coactivator MAL.
about
An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-AMolecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MALTwo novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actinMuscle-specific signaling mechanism that links actin dynamics to serum response factor.Modulation of muscle regeneration, myogenesis, and adipogenesis by the Rho family guanine nucleotide exchange factor GEFT.Nuclear actin and actin-binding proteins in the regulation of transcription and gene expressionDual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodelingMechanisms of Vascular Smooth Muscle Contraction and the Basis for Pharmacologic Treatment of Smooth Muscle DisordersEpithelial sheet movement requires the cooperation of c-Jun and MAP3K1Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain developmentMyocardin-Related Transcription Factor A Activation by Competition with WH2 Domain Proteins for Actin Binding.Inhibition of arginyltransferase 1 induces transcriptional activity of myocardin-related transcription factor A (MRTF-A) and promotes directional migration.Thymosin β4 Improves Differentiation and Vascularization of EHTs.Scapinin, the protein phosphatase 1 binding protein, enhances cell spreading and motility by interacting with the actin cytoskeleton.Activation and repression of cellular immediate early genes by serum response factor cofactors.Actin-mediated gene expression in neurons: the MRTF-SRF connection.Linking actin dynamics and gene transcription to drive cellular motile functions.Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytesLoss of γ-cytoplasmic actin triggers myofibroblast transition of human epithelial cells.SRF binding to SRE 6.9 in the Arc promoter is essential for LTD in cultured Purkinje cellsTranscriptional activity of megakaryoblastic leukemia 1 (MKL1) is repressed by SUMO modification.Increased SRF transcriptional activity in human and mouse skeletal muscle is a signature of insulin resistanceAkt activation induces hypertrophy without contractile phenotypic maturation in airway smooth musclecAMP-induced actin cytoskeleton remodelling inhibits MKL1-dependent expression of the chemotactic and pro-proliferative factor, CCN1.LMO7 mediates cell-specific activation of the Rho-myocardin-related transcription factor-serum response factor pathway and plays an important role in breast cancer cell migration.Cell contact-dependent regulation of epithelial-myofibroblast transition via the rho-rho kinase-phospho-myosin pathway.Nuclear actin and myosins in adenovirus infection.Serum Response Factor (SRF)-cofilin-actin signaling axis modulates mitochondrial dynamics.As functional nuclear actin comes into view, is it globular, filamentous, or both?Serum-induced phosphorylation of the serum response factor coactivator MKL1 by the extracellular signal-regulated kinase 1/2 pathway inhibits its nuclear localization.Cell geometric constraints induce modular gene-expression patterns via redistribution of HDAC3 regulated by actomyosin contractility.A tense situation: forcing tumour progression.Identification, expression and characterization of rat isoforms of the serum response factor (SRF) coactivator MKL1.Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells.Mechanisms of nuclear actin in chromatin-remodeling complexes.Functional analysis of proteins and protein species using shotgun proteomics and linear mathematics.Transcriptional regulation and nuclear reprogramming: roles of nuclear actin and actin-binding proteins.The STARS signaling pathway: a key regulator of skeletal muscle function.Bidirectional Synaptic Structural Plasticity after Chronic Cocaine Administration Occurs through Rap1 Small GTPase Signaling.Interaction between MyRIP and the actin cytoskeleton regulates Weibel-Palade body trafficking and exocytosis
P2860
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P2860
Mutant actins that stabilise F-actin use distinct mechanisms to activate the SRF coactivator MAL.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Mutant actins that stabilise F ...... ivate the SRF coactivator MAL.
@en
type
label
Mutant actins that stabilise F ...... ivate the SRF coactivator MAL.
@en
prefLabel
Mutant actins that stabilise F ...... ivate the SRF coactivator MAL.
@en
P2860
P356
P1433
P1476
Mutant actins that stabilise F ...... ivate the SRF coactivator MAL.
@en
P2093
Francesc Miralles
Guido Posern
P2860
P304
P356
10.1038/SJ.EMBOJ.7600404
P407
P577
2004-09-23T00:00:00Z