Angiotensin II-dependent Src and Smad1 signaling pathway is crucial for the development of diabetic nephropathy. - Wikidata - awgldk - TriplyDB

Angiotensin II-dependent Src and Smad1 signaling pathway is crucial for the development of diabetic nephropathy.

Angiotensin II-dependent Src and Smad1 signaling pathway is crucial for the development of diabetic nephropathy.

http://www.wikidata.org/entity/Q40269064

about

Treatment of diabetic kidney disease: current and future targets.CCN2 is required for the TGF-β induced activation of Smad1-Erk1/2 signaling network Store-Operated Ca2+ Channels in Mesangial Cells Inhibit Matrix Protein Expression.Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: role in mesangial cell hypertrophy and fibronectin expression The selected traditional chinese medicinal formulas for treating diabetic nephropathy: perspective of modern science.STORE OPERATED CALCIUM ENTRY SUPPRESSED TGFβ1-SMAD3 SIGNALING PATHWAY IN GLOMERULAR MESANGIAL CELLS.Canonical Transient Receptor Potential 6 Channel: A New Target of Reactive Oxygen Species in Renal Physiology and Pathology.Src family kinases in chronic kidney disease.Activation of Src mediates PDGF-induced Smad1 phosphorylation and contributes to the progression of glomerulosclerosis in glomerulonephritis.Inhibition of Src kinase blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells and prevents diabetic nephropathy in mice.Negative regulation of Smad1 pathway and collagen IV expression by store-operated Ca2+ entry in glomerular mesangial cells.High glucose activates PKC-zeta and NADPH oxidase through autocrine TGF-beta1 signaling in mesangial cells.Urinary Smad1 is a new biomarker for diagnosis and evaluating the severity of diabetic nephropathy.Roux-en-Y Esophagojejunostomy Ameliorates Renal Function Through Reduction of Renal Inflammatory and Fibrotic Markers in Diabetic Nephropathy.

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P2860

Angiotensin II-dependent Src and Smad1 signaling pathway is crucial for the development of diabetic nephropathy.

http://www.wikidata.org/entity/Q40269064

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Akira Mima

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Atsushi Fukatsu

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Eriko Sumi

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Hideharu Abe

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Hidenori Arai

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Hiroshi Kanamori

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Kojiro Nagai

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Noriyuki Iehara

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Takeshi Matsubara

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Toru Kita

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P2860

Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes

Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice

Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat

A vitamin D analog ameliorates glomerular injury on rat glomerulonephritis

c-Src regulates clathrin adapter protein 2 interaction with beta-arrestin and the angiotensin II type 1 receptor during clathrin- mediated internalization

A multifunctional transcription factor (A1p145) regulates the smooth muscle phenotype in mesangial cells

Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

Type IV collagen is transcriptionally regulated by Smad1 under advanced glycation end product (AGE) stimulation.

The role of angiotensin II and plasminogen activator inhibitor-1 in progressive glomerulosclerosis.

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