Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: role in mesangial cell hypertrophy and fibronectin expression
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The balance of powers: Redox regulation of fibrogenic pathways in kidney injuryTherapeutic targeting of redox signaling in myofibroblast differentiation and age-related fibrotic diseaseNADPH oxidases in lung health and diseaseHepatitis C Virus (HCV) Proteins Induce NADPH Oxidase 4 Expression in a Transforming Growth Factor -Dependent Manner: a New Contributor to HCV-Induced Oxidative StressRole of NADPH Oxidase in Metabolic Disease-Related Renal Injury: An UpdateOxidant Mechanisms in Renal Injury and DiseaseCanonical transient receptor potential 6 (TRPC6), a redox-regulated cation channelNADPH oxidase 1 modulates WNT and NOTCH1 signaling to control the fate of proliferative progenitor cells in the colonNAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts.NOX enzymes and pulmonary disease.Downstream targets and intracellular compartmentalization in Nox signaling.PDK1 recruitment to the SHPS-1 signaling complex enhances insulin-like growth factor-i-stimulated AKT activation and vascular smooth muscle cell survival.Increased oxidative stress in the nucleus caused by Nox4 mediates oxidation of HDAC4 and cardiac hypertrophy.Abundance of TRPC6 protein in glomerular mesangial cells is decreased by ROS and PKC in diabetesQian Yang Yu Yin Granule-containing serum inhibits angiotensin II-induced proliferation, reactive oxygen species production, and inflammation in human mesangial cells via an NADPH oxidase 4-dependent pathway.Upstream regulators and downstream effectors of NADPH oxidases as novel therapeutic targets for diabetic kidney disease.Hyperglycemia enhances IGF-I-stimulated Src activation via increasing Nox4-derived reactive oxygen species in a PKCζ-dependent manner in vascular smooth muscle cells.Myocardin-related Transcription Factor Regulates Nox4 Protein Expression: LINKING CYTOSKELETAL ORGANIZATION TO REDOX STATE.IGF-I increases the expression of fibronectin by Nox4-dependent Akt phosphorylation in renal tubular epithelial cellsActivation of AMP-activated protein kinase prevents TGF-β1-induced epithelial-mesenchymal transition and myofibroblast activation.The NOX toolbox: validating the role of NADPH oxidases in physiology and disease.Store-Operated Ca2+ Channels in Mesangial Cells Inhibit Matrix Protein Expression.Nox4 involvement in TGF-beta and SMAD3-driven induction of the epithelial-to-mesenchymal transition and migration of breast epithelial cells.Role of H(2)O(2) in hypertension, renin-angiotensin system activation and renal medullary disfunction caused by angiotensin II.Hyperglycemia stimulates p62/PKCζ interaction, which mediates NF-κB activation, increased Nox4 expression, and inflammatory cytokine activation in vascular smooth muscleAngiotensin II stimulates superoxide production in the thick ascending limb by activating NOX4.Role of TLR4/NADPH oxidase/ROS-activated p38 MAPK in VCAM-1 expression induced by lipopolysaccharide in human renal mesangial cells.Phosphoinositide-dependent kinase-1 and protein kinase Cδ contribute to endothelin-1 constriction and elevated blood pressure in intermittent hypoxiaRecruitment of Nox4 to a plasma membrane scaffold is required for localized reactive oxygen species generation and sustained Src activation in response to insulin-like growth factor-I.Targeting NOX enzymes in pulmonary fibrosisProlonged fasting activates Nrf2 in post-weaned elephant seals.ADAM17 mediates Nox4 expression and NADPH oxidase activity in the kidney cortex of OVE26 mice.Sestrin 2 and AMPK connect hyperglycemia to Nox4-dependent endothelial nitric oxide synthase uncoupling and matrix protein expression.The angiotensin II-AT1 receptor stimulates reactive oxygen species within the cell nucleus.Nox4 NADPH oxidase mediates peroxynitrite-dependent uncoupling of endothelial nitric-oxide synthase and fibronectin expression in response to angiotensin II: role of mitochondrial reactive oxygen species.Identification of novel SHPS-1-associated proteins and their roles in regulation of insulin-like growth factor-dependent responses in vascular smooth muscle cells.NADPH oxidases and angiotensin II receptor signalingDiabetes and Kidney Disease: Role of Oxidative Stress.Genetic silencing of Nox2 and Nox4 reveals differential roles of these NADPH oxidase homologues in the vasopressor and dipsogenic effects of brain angiotensin II.Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension.
P2860
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P2860
Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: role in mesangial cell hypertrophy and fibronectin expression
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Nox4 NAD(P)H oxidase mediates ...... phy and fibronectin expression
@en
type
label
Nox4 NAD(P)H oxidase mediates ...... phy and fibronectin expression
@en
prefLabel
Nox4 NAD(P)H oxidase mediates ...... phy and fibronectin expression
@en
P2093
P2860
P356
P1476
Nox4 NAD(P)H oxidase mediates ...... phy and fibronectin expression
@en
P2093
Assaad Eid
Duck-Yoon Lee
Karen Block
Yohann Wittrant
P2860
P304
24061-24076
P356
10.1074/JBC.M803964200
P407
P577
2008-06-16T00:00:00Z