PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase.
about
The BRCA1/2 pathway prevents hematologic cancers in addition to breast and ovarian cancersPML nuclear bodiesThe death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3From an old remedy to a magic bullet: molecular mechanisms underlying the therapeutic effects of arsenic in fighting leukemiaDnmt3b Prefers Germ Line Genes and Centromeric Regions: Lessons from the ICF Syndrome and Cancer and Implications for DiseasesHeterochromatin instability in cancer: from the Barr body to satellites and the nuclear peripheryWRN loss induces switching of telomerase-independent mechanisms of telomere elongationSubcellular localization of Daxx determines its opposing functions in ischemic cell deathPML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cellsDynamics of telomeres and promyelocytic leukemia nuclear bodies in a telomerase-negative human cell line.Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylaseDeficiency of the dual ubiquitin/SUMO ligase Topors results in genetic instability and an increased rate of malignancy in mice.Nano-dissection and sequencing of DNA at single sub-nuclear structures.The chromatin remodelling factor dATRX is involved in heterochromatin formationAltered intra-nuclear organisation of heterochromatin and genes in ICF syndrome.Impact of nuclear organization and dynamics on epigenetic regulation in the central nervous system: implications for neurological disease states.HSV-1 genome subnuclear positioning and associations with host-cell PML-NBs and centromeres regulate LAT locus transcription during latency in neurons.Functional reorganization of promyelocytic leukemia nuclear bodies during BK virus infection.RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.Dual functions of histone-lysine N-methyltransferase Setdb1 protein at promyelocytic leukemia-nuclear body (PML-NB): maintaining PML-NB structure and regulating the expression of its associated genes.The Cardiac Stress Response Factor Ms1 Can Bind to DNA and Has a Function in the NucleusA novel cell response triggered by interphase centromere structural instabilitySubcellular distribution of human RDM1 protein isoforms and their nucleolar accumulation in response to heat shock and proteotoxic stressPML nuclear bodies: assembly and oxidative stress-sensitive sumoylation.ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulationAtrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span.A novel single cell method to identify the genetic composition at a single nuclear body.New insights into the role of PML in tumour suppression.Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins.The XNP remodeler targets dynamic chromatin in Drosophila.Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination.Dynamics of histone H3.3 deposition in proliferating and senescent cells reveals a DAXX-dependent targeting to PML-NBs important for pericentromeric heterochromatin organization.JC virus inclusions in progressive multifocal leukoencephalopathy: scaffolding promyelocytic leukemia nuclear bodies grow with cell cycle transition through an S-to-G2-like state in enlarging oligodendrocyte nuclei.Assaying and investigating Alternative Lengthening of Telomeres activity in human cells and cancers.Heterochromatin and the DNA damage response: the need to relax.The nuclear bodies inside out: PML conquers the cytoplasm.Functions of chromatin remodeling factors in heterochromatin formation and maintenance.PML body meets telomere: the beginning of an ALTernate ending?Chromatin maintenance and dynamics in senescence: a spotlight on SAHF formation and the epigenome of senescent cells.Disruption of host antiviral resistances by gammaherpesvirus tegument proteins with homology to the FGARAT purine biosynthesis enzyme
P2860
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P2860
PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
PML nuclear bodies are highly ...... n remodelling at the G2 phase.
@en
type
label
PML nuclear bodies are highly ...... n remodelling at the G2 phase.
@en
prefLabel
PML nuclear bodies are highly ...... n remodelling at the G2 phase.
@en
P2093
P50
P356
P1476
PML nuclear bodies are highly ...... in remodelling at the G2 phase
@en
P2093
Andre Megarbane
Anne Moncla
Catherine Metzler-Guillemain
Cecile Mignon-Ravix
Huseyin Sirma
Jean Feunteun
Judith J Luciani
Pierre Sarda
P304
P356
10.1242/JCS.02965
P407
P577
2006-05-30T00:00:00Z