A proteomic analysis reveals the loss of expression of the cell death regulatory gene GRIM-19 in human renal cell carcinomas.
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Identification and characterization of GRIM-1, a cell-death-associated gene productDown-regulation of the transcriptional mediator subunit Med1 contributes to the loss of expression of metastasis-associated dapk1 in human cancers and cancer cellsTranscriptional activation of the suppressor of cytokine signaling-3 (SOCS-3) gene via STAT3 is increased in F9 REX1 (ZFP-42) knockout teratocarcinoma stem cells relative to wild-type cellsCombined analysis of transcriptome and proteome data as a tool for the identification of candidate biomarkers in renal cell carcinoma.GRIM-19 and p16(INK4a) synergistically regulate cell cycle progression and E2F1-responsive gene expression.NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.GRIM-19 disrupts E6/E6AP complex to rescue p53 and induce apoptosis in cervical cancers.Interferons, signal transduction pathways, and the central nervous system.Identification of a structural motif in the tumor-suppressive protein GRIM-19 required for its antitumor activityGRIM-19 Expression and Function in Human Gliomas.Cytokine-induced tumor suppressors: a GRIM storyDown-regulation of GRIM-19 expression is associated with hyperactivation of STAT3-induced gene expression and tumor growth in human cervical cancers.GRIM-19: A Double-edged Sword that Regulates Anti-Tumor and Innate Immune Responses.Rapid identification of Vibrio parahaemolyticus isolated from shellfish, sea water and sediments of the Khnifiss lagoon, Morocco, by MALDI-TOF mass spectrometry.Suppression of mitochondrial complex I influences cell metastatic properties.Overexpression of GRIM-19, a mitochondrial respiratory chain complex I protein, suppresses hepatocellular carcinoma growth.Decreased expression of GRIM-19 by DNA hypermethylation promotes aerobic glycolysis and cell proliferation in head and neck squamous cell carcinoma.Tumor suppressive protein gene associated with retinoid-interferon-induced mortality (GRIM)-19 inhibits src-induced oncogenic transformation at multiple levels.Tumor-derived mutations in the gene associated with retinoid interferon-induced mortality (GRIM-19) disrupt its anti-signal transducer and activator of transcription 3 (STAT3) activity and promote oncogenesis.Plasmid-based Survivin shRNA and GRIM-19 carried by attenuated Salmonella suppresses tumor cell growth.GRIM-19 inhibits v-Src-induced cell motility by interfering with cytoskeletal restructuring.Small interfering RNA survivin and GRIM-19 co-expression salmonella plasmid inhibited the growth of laryngeal cancer cells in vitro and in vivo.Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice.Mitochondrial GRIM-19 as a potential therapeutic target for STAT3-dependent carcinogenesis of gastric cancer.GRIM-19 mutations fail to inhibit v-Src-induced oncogenesis.GRIM-19 Restricts HCV Replication by Attenuating Intracellular Lipid Accumulation.Accessory subunits of mitochondrial complex I.Gene associated with retinoid-interferon-induced mortality 19 attenuates murine autoimmune arthritis by regulation of th17 and treg cells.GRIM-19: A master regulator of cytokine induced tumor suppression, metastasis and energy metabolism.Oncogenic K-ras expression is associated with derangement of the cAMP/PKA pathway and forskolin-reversible alterations of mitochondrial dynamics and respiration.Depletion of GRIM-19 accelerates hepatocellular carcinoma invasion via inducing EMT and loss of contact inhibition.Differential effects of all-trans retinoic acid on the growth of human keratinocytes and mouth carcinoma epidermoid cultures. Involvement of GRIM-19 and complex I of the respiratory chain.Electron leak from NDUFA13 within mitochondrial complex I attenuates ischemia-reperfusion injury via dimerized STAT3.Identification of alternatively spliced GRIM-19 mRNA in kidney cancer tissues.Downregulation of GRIM-19 promotes growth and migration of human glioma cells.miR-6743-5p, as a direct upstream regulator of GRIM-19, enhances proliferation and suppresses apoptosis in glioma cells.The Oncojanus Paradigm of Respiratory Complex I.Renal Cell Carcinoma: Molecular AspectsMitochondrial Markers for Cancer: Relevance to Diagnosis, Therapy, and Prognosis and General Understanding of Malignant Disease Mechanisms
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A proteomic analysis reveals the loss of expression of the cell death regulatory gene GRIM-19 in human renal cell carcinomas.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
A proteomic analysis reveals t ...... n human renal cell carcinomas.
@en
type
label
A proteomic analysis reveals t ...... n human renal cell carcinomas.
@en
prefLabel
A proteomic analysis reveals t ...... n human renal cell carcinomas.
@en
P2093
P2860
P356
P1433
P1476
A proteomic analysis reveals t ...... n human renal cell carcinomas.
@en
P2093
Alchanati I
Kalvakolanu DV
Konforty D
Resnick MB
P2860
P2888
P304
P356
10.1038/SJ.ONC.1209708
P407
P577
2006-05-29T00:00:00Z
P5875
P6179
1046359336