Glucocorticoid resistance in squirrel monkeys results from a combination of a transcriptionally incompetent glucocorticoid receptor and overexpression of the glucocorticoid receptor co-chaperone FKBP51.
about
Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90Chrousos syndrome: a seminal report, a phylogenetic enigma and the clinical implications of glucocorticoid signalling changesA new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51.Reverse translational strategies for developing animal models of bipolar disorder.Is FKBP5 a genetic marker of affective psychosis? A case control study and analysis of disease related traits.Glucocorticoid-regulated genes in eosinophilic esophagitis: a role for FKBP51.Short-term recognition memory impairment is associated with decreased expression of FK506 binding protein 51 in the aged mouse brain.Differential expression of immunophilins FKBP51 and FKBP52 in the frontal cortex of HIV-infected patients with major depressive disorder.Dose- and time-dependent glucocorticoid receptor signaling in podocytes.The developmental impact of prenatal stress, prenatal dexamethasone and postnatal social stress on physiology, behaviour and neuroanatomy of primate offspring: studies in rhesus macaque and common marmoset.What goes on behind closed doors: physiological versus pharmacological steroid hormone actions.Versatile TPR domains accommodate different modes of target protein recognition and functionDepletion of FKBP51 in female mice shapes HPA axis activity.FKBP51-a selective modulator of glucocorticoid and androgen sensitivity.FKBP5 variation is associated with the acute and chronic effects of nicotineCross-cultural gene- environment interactions in depression, post-traumatic stress disorder, and the cortisol awakening response: FKBP5 polymorphisms and childhood trauma in South Asia.Environmental Enrichment Increases Glucocorticoid Receptors and Decreases GluA2 and Protein Kinase M Zeta (PKMζ) Trafficking During Chronic Stress: A Protective Mechanism?Synergistic Effects of Calcineurin Inhibitors and Steroids on Steroid Sensitivity of Peripheral Blood Mononuclear Cells.BAG1 plays a critical role in regulating recovery from both manic-like and depression-like behavioral impairments.FK506-binding protein 51 regulates nuclear transport of the glucocorticoid receptor beta and glucocorticoid responsivenessLong-term low level glucocorticoid exposure induces persistent repression in chromatin.Molecular mechanisms regulating glucocorticoid sensitivity and resistance.Protein-protein interactions enable rapid adaptive response to osmotic stress in fish gills.Androgen resistance in squirrel monkeys (Saimiri spp.).Dysregulation of glucocorticoid receptor co-factors FKBP5, BAG1 and PTGES3 in prefrontal cortex in psychotic illness.Higher Sensitivity of Peripheral Blood Lymphocytes to Endogenous Glucocorticoid in Renal Transplant Recipients Treated With Tacrolimus, as Compared to Those Treated With CyclosporineThe impact of genetic factors on response to glucocorticoids therapy in IBD.Glucocorticoid therapy and ocular hypertension.Regulation of store-operated calcium entry by FK506-binding immunophilinsThe prospect of FKBP51 as a drug target.Validation of a radioimmunoassay for measuring testosterone concentrations in plasma samples of the subterranean rodent Ctenomys talarum: outstandingly elevated levels in the wild and the effect of captivity.Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD
P2860
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P2860
Glucocorticoid resistance in squirrel monkeys results from a combination of a transcriptionally incompetent glucocorticoid receptor and overexpression of the glucocorticoid receptor co-chaperone FKBP51.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Glucocorticoid resistance in s ...... receptor co-chaperone FKBP51.
@en
type
label
Glucocorticoid resistance in s ...... receptor co-chaperone FKBP51.
@en
prefLabel
Glucocorticoid resistance in s ...... receptor co-chaperone FKBP51.
@en
P2093
P1476
Glucocorticoid resistance in s ...... receptor co-chaperone FKBP51.
@en
P2093
J M Westberry
Jonathan G Scammell
P W Sadosky
T R Hubler
P356
10.1016/J.JSBMB.2006.03.004
P577
2006-05-24T00:00:00Z