Synthesis, biological activity, and DNA-damage profile of platinum-threading intercalator conjugates designed to target adenine.
about
Gold(I) analogues of a platinum-acridine antitumor agent are only moderately cytotoxic but show potent activity against Mycobacterium tuberculosisThe Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) ProdrugsComparative chemogenomics to examine the mechanism of action of dna-targeted platinum-acridine anticancer agentsThe challenge of deciphering linkage isomers in mixtures of oligomeric complexes derived from 9-methyladenine and trans-(NH3)2Pt(II) units.Synthesis and biological evaluation of platinum-acridine hybrid agents modified with bipyridine non-leaving groups.Probing platinum-adenine-n3 adduct formation with DNA minor-groove binding agentsSynthesis, characterization and cytotoxicity studies of palladium(II)-proflavine complexesRates of intercalator-driven platination of DNA determined by a restriction enzyme cleavage inhibition assay.Human Serum Albumin-Delivered [Au(PEt3)]+ Is a Potent Inhibitor of T Cell Proliferation.Effect of linkage geometry on biological activity in thiourea- and guanidine-substituted acridines and platinum-acridines.Tuning the DNA conformational perturbations induced by cytotoxic platinum-acridine bisintercalators: effect of metal cis/trans isomerism and DNA threading groups.A non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer.Atomistic-level portrayal of drug-DNA Interplay: a history of courtships and meetings revealed by molecular simulations.Target-selective delivery and activation of platinum-based anticancer agents.Nucleotide Binding Preference of the Monofunctional Platinum Anticancer-Agent Phenanthriplatin.Complexes of Pd(II) and Pt(II) with 9-aminoacridine: reactions with DNA and study of their antiproliferative activity.
P2860
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P2860
Synthesis, biological activity, and DNA-damage profile of platinum-threading intercalator conjugates designed to target adenine.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Synthesis, biological activity ...... es designed to target adenine.
@en
type
label
Synthesis, biological activity ...... es designed to target adenine.
@en
prefLabel
Synthesis, biological activity ...... es designed to target adenine.
@en
P2093
P356
P1476
Synthesis, biological activity ...... es designed to target adenine.
@en
P2093
Gilda Saluta
Gregory L Kucera
Rajsekhar Guddneppanavar
Ulrich Bierbach
P304
P356
10.1021/JM060035V
P407
P577
2006-06-01T00:00:00Z