Downregulation of PIK3CB by siRNA suppresses malignant glioma cell growth in vitro and in vivo.
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Should individual PI3 kinase isoforms be targeted in cancer?PIK3CA and PIK3CB inhibition produce synthetic lethality when combined with estrogen deprivation in estrogen receptor-positive breast cancer.Human cytomegalovirus inhibits apoptosis by regulating the activating transcription factor 5 signaling pathway in human malignant glioma cells.Recognizing and exploiting differences between RNAi and small-molecule inhibitors.The different role of Notch1 and Notch2 in astrocytic gliomasArtemether combined with shRNA interference of vascular cell adhesion molecule-1 significantly inhibited the malignant biological behavior of human glioma cells.Downregulation of PI3Kcb utilizing adenovirus-mediated transfer of siRNA attenuates bone cancer pain.Downregulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth.Phosphoinositide 3-kinases p110alpha and p110beta regulate cell cycle entry, exhibiting distinct activation kinetics in G1 phase.A novel therapeutic strategy for the treatment of glioma, combining chemical and molecular targeting of hsp90a.Signal transduction molecule patterns indicating potential glioblastoma therapy approaches.Silencing of NRAGE induces autophagy via AMPK/Ulk1/Atg13 signaling pathway in NSCLC cells.Down-regulation of p110β expression increases chemosensitivity of colon cancer cell lines to oxaliplatin.Resveratrol downregulates PI3K/Akt/mTOR signaling pathways in human U251 glioma cells.PTEN restoration and PIK3CB knockdown synergistically suppress glioblastoma growth in vitro and in xenografts.IL-6 promotion of glioblastoma cell invasion and angiogenesis in U251 and T98G cell lines.The oncogenic roles of Notch1 in astrocytic gliomas in vitro and in vivo.Combination gene therapy with PTEN and EGFR siRNA suppresses U251 malignant glioma cell growth in vitro and in vivo.Construction of a recombinant lentivirus containing human microRNA-7-3 and its inhibitory effects on glioma proliferation.PIK3CB/p110β is a Selective Survival Factor for Glioblastoma.The Role of Class IA Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunits in Glioblastoma.TGX-221 inhibits proliferation and induces apoptosis in human glioblastoma cells.An Efficient Bivalent Cyclic RGD-PIK3CB siRNA Conjugate for Specific Targeted Therapy against Glioblastoma In Vitro and In Vivo
P2860
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P2860
Downregulation of PIK3CB by siRNA suppresses malignant glioma cell growth in vitro and in vivo.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Downregulation of PIK3CB by si ...... l growth in vitro and in vivo.
@en
type
label
Downregulation of PIK3CB by si ...... l growth in vitro and in vivo.
@en
prefLabel
Downregulation of PIK3CB by si ...... l growth in vitro and in vivo.
@en
P2093
P2860
P1476
Downregulation of PIK3CB by si ...... l growth in vitro and in vivo.
@en
P2093
Chunsheng Kang
Xiaozhi Liu
Zhiyong Zhang
P2860
P304
P356
10.1177/153303460600500308
P577
2006-06-01T00:00:00Z