The role of cholesterol in the activity of pneumolysin, a bacterial protein toxin.
about
The solution structure and oligomerization behavior of two bacterial toxins: pneumolysin and perfringolysin O.Conformational changes that effect oligomerization and initiate pore formation are triggered throughout perfringolysin O upon binding to cholesterol.The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activityPerfringolysin O: The Underrated Clostridium perfringens Toxin?Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation.β-sitosterol interacts with pneumolysin to prevent Streptococcus pneumoniae infection.Insights into structure and activity of natural compound inhibitors of pneumolysin.Use of a Cholesterol Recognition Amino Acid Consensus Peptide To Inhibit Binding of a Bacterial Toxin to Cholesterol.Measuring kinetic drivers of pneumolysin pore structure.Structure-guided antigen engineering yields pneumolysin mutants suitable for vaccination against pneumococcal disease.Cholesterol binding by the bacterial type III translocon is essential for virulence effector delivery into mammalian cells.The mechanism of pneumolysin-induced cochlear hair cell death in the rat.Synthesis of deuterated [D32 ]oleic acid and its phospholipid derivative [D64 ]dioleoyl-sn-glycero-3-phosphocholine.
P2860
Q34186321-2922380A-139B-4969-801A-E6637E886DB1Q34635171-1E4B9A96-4AF7-4C9D-BA1C-B5E2C63D88D9Q34709412-C9B7FBC8-0586-4218-B297-2B6C4791DE7EQ35662926-E13DAC41-4652-4F22-BC6B-120CB1F46CE8Q36099951-A2F446BD-4C37-45BF-BBB9-842BE0F863B8Q36343349-F495BA9C-49FA-4492-A4D7-F8C05736C32BQ37625776-7E751E0E-439A-4FEC-833F-712F8D40442CQ38752907-FCE9C273-DA69-4486-A941-219D86CF9984Q39931955-C940C54F-0D72-4B18-837B-57C1308A3453Q42708867-10A0746D-9D5B-466A-81E7-E75762F42ED6Q42816094-048B8D47-C6E6-4B55-92D6-DF39A323B856Q46624496-1B42B765-3E00-4B40-80C4-DF99E45D436BQ54523355-C28A1252-60E2-4E1F-921F-ACA9801C8C8C
P2860
The role of cholesterol in the activity of pneumolysin, a bacterial protein toxin.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The role of cholesterol in the activity of pneumolysin, a bacterial protein toxin.
@en
type
label
The role of cholesterol in the activity of pneumolysin, a bacterial protein toxin.
@en
prefLabel
The role of cholesterol in the activity of pneumolysin, a bacterial protein toxin.
@en
P2860
P50
P1433
P1476
The role of cholesterol in the activity of pneumolysin, a bacterial protein toxin
@en
P2093
Michele Sferrazza
Olwyn Byron
P2860
P304
P356
10.1016/S0006-3495(04)74362-3
P407
P577
2004-05-01T00:00:00Z