Cortactin underpins CD44-promoted invasion and adhesion of breast cancer cells to bone marrow endothelial cells. - Wikidata - awgldk - TriplyDB

Cortactin underpins CD44-promoted invasion and adhesion of breast cancer cells to bone marrow endothelial cells.

Cortactin underpins CD44-promoted invasion and adhesion of breast cancer cells to bone marrow endothelial cells.

http://www.wikidata.org/entity/Q40284719

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Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cells Arg interacts with cortactin to promote adhesion-dependent cell edge protrusion WNT5A signaling impairs breast cancer cell migration and invasion via mechanisms independent of the epithelial-mesenchymal transition HER2 carboxyl-terminal fragments regulate cell migration and cortactin phosphorylation Interlobular and intralobular mammary stroma: genotype may not reflect phenotype Nuclear beta-catenin and CD44 upregulation characterize invasive cell populations in non-aggressive MCF-7 breast cancer cells.FKBPL and peptide derivatives: novel biological agents that inhibit angiogenesis by a CD44-dependent mechanism.In vivo evidence for the role of CD44s in promoting breast cancer metastasis to the liver.Cortactin: a multifunctional regulator of cellular invasiveness Survivin is a novel target of CD44-promoted breast tumor invasion CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis Chansu inhibits the expression of cortactin in colon cancer cell lines in vitro and in vivo.CD44 increases the efficiency of distant metastasis of breast cancer Src tyrosyl phosphorylates cortactin in response to prolactin.Significance of CD44 and CD24 as cancer stem cell markers: an enduring ambiguity CD44 and beta3 integrin organize two functionally distinct actin-based domains in osteoclasts CD44 enhances invasion of basal-like breast cancer cells by upregulating serine protease and collagen-degrading enzymatic expression and activity.Functional heterogeneity within the CD44 high human breast cancer stem cell-like compartment reveals a gene signature predictive of distant metastasis Lipid raft association restricts CD44-ezrin interaction and promotion of breast cancer cell migration.Prognostic significance of cortactin levels in head and neck squamous cell carcinoma: comparison with epidermal growth factor receptor status Nav1.5 regulates breast tumor growth and metastatic dissemination in vivo CD44-mediated activation of α5β1-integrin, cortactin and paxillin signaling underpins adhesion of basal-like breast cancer cells to endothelium and fibronectin-enriched matrices.Separation and Characterization of Epithelial and Mesenchymal-like Murine Mammary Tumor Cells Reveals Epithelial Cell Differentiation Plasticity and Enhanced Tumorigenicity of Epithelial-enriched Tumor Cells.Cortactin is a sensitive biomarker relative to the poor prognosis of human hepatocellular carcinoma.In vivo monitoring of CD44+ cancer stem-like cells by γ-irradiation in breast cancer.Bone marrow micrometastasis in breast cancer: review of detection methods, prognostic impact and biological issues.Hyaluronan, CD44 and Emmprin: partners in cancer cell chemoresistance.Regulation of CD44 expression and focal adhesion by Golgi phosphatidylinositol 4-phosphate in breast cancer.A new role for cortactin in invadopodia: regulation of protease secretion.Cortactin in tumor invasiveness.Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry.Virtual screening-driven repositioning of etoposide as CD44 antagonist in breast cancer cells Simultaneous inhibition of cell-cycle, proliferation, survival, metastatic pathways and induction of apoptosis in breast cancer cells by a phytochemical super-cocktail: genes that underpin its mode of action.CD44 targets Na(+)/H(+) exchanger 1 to mediate MDA-MB-231 cells' metastasis via the regulation of ERK1/2.Hyaluronan: a simple polysaccharide with diverse biological functions.Cortactin expression confers a more malignant phenotype to gastric cancer SGC-7901 cells.BRCA1-IRIS overexpression promotes and maintains the tumor initiating phenotype: implications for triple negative breast cancer early lesions.Cortactin in cell migration and cancer at a glance When Good Turns Bad: Regulation of Invasion and Metastasis by ErbB2 Receptor Tyrosine Kinase.

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Cortactin underpins CD44-promoted invasion and adhesion of breast cancer cells to bone marrow endothelial cells.

http://www.wikidata.org/entity/Q40284719

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2006 nî lūn-bûn

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Cortactin underpins CD44-promo ...... bone marrow endothelial cells.

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Cortactin underpins CD44-promo ...... bone marrow endothelial cells.

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Cortactin underpins CD44-promo ...... bone marrow endothelial cells.

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P2860

Activation of Arp2/3 complex-mediated actin polymerization by cortactin

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway

Prospective identification of tumorigenic breast cancer cells

Cortactin overexpression results in sustained epidermal growth factor receptor signaling by preventing ligand-induced receptor degradation in human carcinoma cells.

CD44 interaction with c-Src kinase promotes cortactin-mediated cytoskeleton function and hyaluronic acid-dependent ovarian tumor cell migration

Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation

Phosphorylation of N-cadherin-associated cortactin by Fer kinase regulates N-cadherin mobility and intercellular adhesion strength.

Breast cancer metastasis to bone: mechanisms of osteolysis and implications for therapy.

How WASP-family proteins and the Arp2/3 complex convert intracellular signals into cytoskeletal structures.

CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration.

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