A new role for cortactin in invadopodia: regulation of protease secretion.
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The regulation of MMP targeting to invadopodia during cancer metastasisMass spectrometric analysis identifies a cortactin-RCC2/TD60 interaction in mitotic cellsThe 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and functionTumor and stromal-based contributions to head and neck squamous cell carcinoma invasionThe interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasionLysine post-translational modifications and the cytoskeletonCells assemble invadopodia-like structures and invade into matrigel in a matrix metalloprotease dependent manner in the circular invasion assayPodoplanin mediates ECM degradation by squamous carcinoma cells through control of invadopodia stabilityArg interacts with cortactin to promote adhesion-dependent cell edge protrusionSrc-mediated phosphorylation of mammalian Abp1 (DBNL) regulates podosome rosette formation in transformed fibroblastsMet receptor tyrosine kinase signals through a cortactin-Gab1 scaffold complex, to mediate invadopodiaSupervillin reorganizes the actin cytoskeleton and increases invadopodial efficiency.The membrane-associated protein, supervillin, accelerates F-actin-dependent rapid integrin recycling and cell motility.STIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion.Cortactin promotes exosome secretion by controlling branched actin dynamicsGelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascadeCortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemiah3/Acidic calponin: an actin-binding protein that controls extracellular signal-regulated kinase 1/2 activity in nonmuscle cellsc-Src differentially regulates the functions of microtentacles and invadopodia.Src-dependent Tks5 phosphorylation regulates invadopodia-associated invasion in prostate cancer cellsSaracatinib Impairs Head and Neck Squamous Cell Carcinoma Invasion by Disrupting Invadopodia FunctionCortactin modulates RhoA activation and expression of Cip/Kip cyclin-dependent kinase inhibitors to promote cell cycle progression in 11q13-amplified head and neck squamous cell carcinoma cells.Cdc42-interacting protein 4 promotes breast cancer cell invasion and formation of invadopodia through activation of N-WASp.Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation.Regulation of synaptojanin 2 5'-phosphatase activity by SrcAbl kinases are required for invadopodia formation and chemokine-induced invasion.Localizing matrix metalloproteinase activities in the pericellular environment.Molecular changes in invasive front of oral cancer.An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion.The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancerRab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells.Cortactin: a multifunctional regulator of cellular invasivenessCD26 expression on T-anaplastic large cell lymphoma (ALCL) line Karpas 299 is associated with increased expression of versican and MT1-MMP and enhanced adhesionTargeting tumor cell motility to prevent metastasis.Toca-1 is suppressed by p53 to limit breast cancer cell invasion and tumor metastasis.Cortactin phosphorylation regulates cell invasion through a pH-dependent pathwayThe Oncogenic Response to MiR-335 Is Associated with Cell Surface Expression of Membrane-Type 1 Matrix Metalloproteinase (MT1-MMP) Activity.Persistent Morbillivirus Infection Leads to Altered Cortactin Distribution in Histiocytic Sarcoma Cells with Decreased Cellular Migration CapacityCoronin 3 promotes gastric cancer metastasis via the up-regulation of MMP-9 and cathepsin K.Matrix rigidity differentially regulates invadopodia activity through ROCK1 and ROCK2.
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A new role for cortactin in invadopodia: regulation of protease secretion.
description
article científic
@ca
article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 14 March 2008
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
A new role for cortactin in invadopodia: regulation of protease secretion.
@en
A new role for cortactin in invadopodia: regulation of protease secretion.
@nl
type
label
A new role for cortactin in invadopodia: regulation of protease secretion.
@en
A new role for cortactin in invadopodia: regulation of protease secretion.
@nl
prefLabel
A new role for cortactin in invadopodia: regulation of protease secretion.
@en
A new role for cortactin in invadopodia: regulation of protease secretion.
@nl
P2860
P1476
A new role for cortactin in invadopodia: regulation of protease secretion.
@en
P2093
Emily S Clark
P2860
P304
P356
10.1016/J.EJCB.2008.01.008
P577
2008-03-14T00:00:00Z