Cyclophilin A renders human immunodeficiency virus type 1 sensitive to Old World monkey but not human TRIM5 alpha antiviral activity.
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Restriction of retroviral replication by APOBEC3G/F and TRIM5alphaIndependent evolution of an antiviral TRIMCyp in rhesus macaquesGain-of-Sensitivity Mutations in a Trim5-Resistant Primary Isolate of Pathogenic SIV Identify Two Independent Conserved Determinants of Trim5α SpecificityPolymorphisms in the regulatory region of the Cyclophilin A gene influence the susceptibility for HIV-1 infectionGene expression analysis of a panel of cell lines that differentially restrict HIV-1 CA mutants infection in a cyclophilin a-dependent mannerCyclophilins and nucleoporins are required for infection mediated by capsids from circulating HIV-2 primary isolates.Interfering residues narrow the spectrum of MLV restriction by human TRIM5alpha.Multiple sites in the N-terminal half of simian immunodeficiency virus capsid protein contribute to evasion from rhesus monkey TRIM5α-mediated restriction.Delaying reverse transcription does not increase sensitivity of HIV-1 to human TRIM5α.Homology-based identification of capsid determinants that protect HIV1 from human TRIM5α restrictionProteasome inhibition reveals that a functional preintegration complex intermediate can be generated during restriction by diverse TRIM5 proteins.A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection.Generation of HIV-1 derivatives that productively infect macaque monkey lymphoid cellsModulation of TRIM5alpha activity in human cells by alternatively spliced TRIM5 isoforms.Role of TRIM5α RING domain E3 ubiquitin ligase activity in capsid disassembly, reverse transcription blockade, and restriction of simian immunodeficiency virus.Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infectionHost cell species-specific effect of cyclosporine A on simian immunodeficiency virus replication.HIV Restriction Factors and Mechanisms of Evasion.Mycobacterium tuberculosis Peptidyl-Prolyl Isomerases Also Exhibit Chaperone like Activity In-Vitro and In-VivoHost factors influencing susceptibility to HIV infection and AIDS progression.A Novel Entry/Uncoating Assay Reveals the Presence of at Least Two Species of Viral Capsids During Synchronized HIV-1 Infection.Preclinical Assessment of Mutant Human TRIM5α as an Anti-HIV-1 TransgeneAnalysis of human cell heterokaryons demonstrates that target cell restriction of cyclosporine-resistant human immunodeficiency virus type 1 mutants is genetically dominant.Identification of an arsenic-sensitive block to primate lentiviral infection of human dendritic cells.Cell factors stimulate human immunodeficiency virus type 1 reverse transcription in vitroBreaking Barriers to an AIDS Model with Macaque-Tropic HIV-1 Derivatives.The control of viral infection by tripartite motif proteins and cyclophilin A.Heterogeneous susceptibility of circulating SIV isolate capsids to HIV-interacting factorsModulation of HIV-1 infectivity and cyclophilin A-dependence by Gag sequence and target cell typePressure from TRIM5α contributes to control of HIV-1 replication by individuals expressing protective HLA-B alleles.A New World primate deficient in tetherin-mediated restriction of human immunodeficiency virus type 1.Target cell type-dependent modulation of human immunodeficiency virus type 1 capsid disassembly by cyclophilin A.Gene therapy strategies to exploit TRIM derived restriction factors against HIV-1.Human immunodeficiency virus, restriction factors, and interferon.Cyclophilins as modulators of viral replication.Viral and cellular requirements for the nuclear entry of retroviral preintegration nucleoprotein complexes.Determinants of cyclophilin A-dependent TRIM5 alpha restriction against HIV-1The innate immune roles of host factors TRIM5α and Cyclophilin A on HIV-1 replication.Cyclophilin A potentiates TRIM5α inhibition of HIV-1 nuclear import without promoting TRIM5α binding to the viral capsid.Cyclophilin A interacts with diverse lentiviral capsids.
P2860
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P2860
Cyclophilin A renders human immunodeficiency virus type 1 sensitive to Old World monkey but not human TRIM5 alpha antiviral activity.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Cyclophilin A renders human im ...... RIM5 alpha antiviral activity.
@en
type
label
Cyclophilin A renders human im ...... RIM5 alpha antiviral activity.
@en
prefLabel
Cyclophilin A renders human im ...... RIM5 alpha antiviral activity.
@en
P2860
P1433
P1476
Cyclophilin A renders human im ...... TRIM5 alpha antiviral activity
@en
P2093
Laura M J Ylinen
Zuzana Keckesova
P2860
P304
P356
10.1128/JVI.80.10.4683-4690.2006
P407
P50
P577
2006-05-01T00:00:00Z