Activated double-stranded RNA-dependent protein kinase and neuronal death in models of Alzheimer's disease.
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mTOR-dependent signalling in Alzheimer's diseaseThe oxindole/imidazole derivative C16 reduces in vivo brain PKR activationExpression and cellular localization of microRNA-29b and RAX, an activator of the RNA-dependent protein kinase (PKR), in the retina of streptozotocin-induced diabetic ratsInhibition of ATF-3 expression by B-Raf mediates the neuroprotective action of GW5074Interaction of double-stranded RNA-dependent protein kinase (PKR) with the death receptor signaling pathway in amyloid beta (Abeta)-treated cells and in APPSLPS1 knock-in micePERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease.Sex- and brain region-specific acceleration of β-amyloidogenesis following behavioral stress in a mouse model of Alzheimer's disease.Transcriptional and epigenetic substrates of methamphetamine addiction and withdrawal: evidence from a long-access self-administration model in the rat.Deletion of the eIF2α Kinase GCN2 fails to rescue the memory decline associated with Alzheimer's disease.Translational control in synaptic plasticity and cognitive dysfunctionRequirement for protein kinase R in interleukin-1alpha-stimulated effects in cartilage.Concurrence of High Fat Diet and APOE Gene Induces Allele Specific Metabolic and Mental Stress Changes in a Mouse Model of Alzheimer's Disease.PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's diseaseER-stress in Alzheimer's disease: turning the scale?The Specific Protein Kinase R (PKR) Inhibitor C16 Protects Neonatal Hypoxia-Ischemia Brain Damages by Inhibiting Neuroinflammation in a Neonatal Rat Model.Roles of eIF2α kinases in the pathogenesis of Alzheimer's disease.Translational control by eIF2α in neurons: Beyond the stress response.Dysregulated mTORC1-Dependent Translational Control: From Brain Disorders to Psychoactive Drugs.The PKR activator PACT is induced by Aβ: involvement in Alzheimer's disease.Lithium chloride and staurosporine potentiate the accumulation of phosphorylated glycogen synthase kinase 3β/Tyr216, resulting in glycogen synthase kinase 3β activation in SH-SY5Y human neuroblastoma cell lines.Basal levels of eIF2alpha phosphorylation determine cellular antioxidant status by regulating ATF4 and xCT expression.ER Stress and Neurodegenerative Disease: A Cause or Effect Relationship?Chronically stressed or stress-preconditioned neurons fail to maintain stress granule assembly.PKR involvement in Alzheimer's diseasePrevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures.Small molecule kinase inhibitors alleviate different molecular features of myotonic dystrophy type 1.PKR downregulation prevents neurodegeneration and β-amyloid production in a thiamine-deficient model.Could PKR inhibition modulate human neurodegeneration?PKR, a cognitive decline biomarker, can regulate translation via two consecutive molecular targets p53 and Redd1 in lymphocytes of AD patients.Regulation of mRNA Translation in Neurons-A Matter of Life and Death.A comprehensive study on long-term injury to nigral dopaminergic neurons following intracerebroventricular injection of lipopolysaccharide in rats.Dissecting Endoplasmic Reticulum Unfolded Protein Response (UPRER) in Managing Clandestine Modus Operandi of Alzheimer's Disease.APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R
P2860
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P2860
Activated double-stranded RNA-dependent protein kinase and neuronal death in models of Alzheimer's disease.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Activated double-stranded RNA- ...... models of Alzheimer's disease.
@en
type
label
Activated double-stranded RNA- ...... models of Alzheimer's disease.
@en
prefLabel
Activated double-stranded RNA- ...... models of Alzheimer's disease.
@en
P2093
P1433
P1476
Activated double-stranded RNA- ...... models of Alzheimer's disease.
@en
P2093
Lafay-Chebassier C
Perault Pochat MC
Rioux Bilan A
P304
P356
10.1016/J.NEUROSCIENCE.2006.01.047
P407
P577
2006-04-03T00:00:00Z