Protein serine/threonine phosphatase-1 dephosphorylates p53 at Ser-15 and Ser-37 to modulate its transcriptional and apoptotic activities.
about
Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localizationTGF-β cascade regulation by PPP1 and its interactors -impact on prostate cancer development and therapyPP2A: The Wolf in Sheep's Clothing?Identification of the WNK-SPAK/OSR1 signaling pathway in rodent and human lensesTranscriptional regulation of PP2A-A alpha is mediated by multiple factors including AP-2alpha, CREB, ETS-1, and SP-1Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins.Acetylation of apurinic/apyrimidinic endonuclease-1 regulates Helicobacter pylori-mediated gastric epithelial cell apoptosisDynamics of p53 and NF-κB regulation in response to DNA damage and identification of target proteins suitable for therapeutic intervention.Drosophila Uri, a PP1alpha binding protein, is essential for viability, maintenance of DNA integrity and normal transcriptional activity.Phosphatases in the cellular response to DNA damage.EDD inhibits ATM-mediated phosphorylation of p53.Differential expression of the catalytic subunits for PP-1 and PP-2A and the regulatory subunits for PP-2A in mouse eye.p53 regulation upon genotoxic stress: intricacies and complexities.Serine/threonine phosphatases in the DNA damage response and cancer.Regulation of DNA fragmentation: the role of caspases and phosphorylation.Transcriptional Regulation of the p53 Tumor Suppressor Gene in S-Phase of the Cell-Cycle and the Cellular Response to DNA Damage.FoxO proteins mediate hypoxic induction of connective tissue growth factor in endothelial cellsThe viral tropism of two distinct oncolytic viruses, reovirus and myxoma virus, is modulated by cellular tumor suppressor gene status.Regulation of p53 expression, phosphorylation and subcellular localization by a G-protein-coupled receptor.Identification of a protective role for protein phosphatase 1cgamma1 against oxidative stress-induced vascular smooth muscle cell apoptosis.Angiogenin functionally interacts with p53 and regulates p53-mediated apoptosis and cell survival.Developmental expression of three small GTPases in the mouse eye.Response to DNA damage: why do we need to focus on protein phosphatases?Okadaic acid induces DNA fragmentation via caspase-3-dependent and caspase-3-independent pathways in Chinese hamster ovary (CHO)-K1 cells.Protein phosphatase-1 modulates the function of Pax-6, a transcription factor controlling brain and eye development.Role and regulation of Glycogen synthase kinase-3 beta in bovine spermatozoa.Role of Protein Phosphatase 1 and Inhibitor of Protein Phosphatase 1 in Nitric Oxide-Dependent Inhibition of the DNA Damage Response in Pancreatic β-Cells.
P2860
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P2860
Protein serine/threonine phosphatase-1 dephosphorylates p53 at Ser-15 and Ser-37 to modulate its transcriptional and apoptotic activities.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Protein serine/threonine phosp ...... onal and apoptotic activities.
@en
type
label
Protein serine/threonine phosp ...... onal and apoptotic activities.
@en
prefLabel
Protein serine/threonine phosp ...... onal and apoptotic activities.
@en
P2093
P356
P1433
P1476
Protein serine/threonine phosp ...... ional and apoptotic activities
@en
P2093
P C Schmid
R Schlosser
P2888
P304
P356
10.1038/SJ.ONC.1209334
P407
P577
2006-05-01T00:00:00Z
P5875
P6179
1026448263