Incorporation of nonmethyl branches by isoprenoid-like logic: multiple beta-alkylation events in the biosynthesis of myxovirescin A1.
about
Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branchingStructure of the Bifunctional Acyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double-Hot-Dog FoldA conserved motif flags acyl carrier proteins for β-branching in polyketide synthesisSingle cell genome amplification accelerates identification of the apratoxin biosynthetic pathway from a complex microbial assemblageIn vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont.Oxazolomycin biosynthesis in Streptomyces albus JA3453 featuring an "acyltransferase-less" type I polyketide synthase that incorporates two distinct extender unitsMetamorphic enzyme assembly in polyketide diversification.Natural products version 2.0: connecting genes to molecules.Myxobacterium-produced antibiotic TA (myxovirescin) inhibits type II signal peptidaseInsights from the sea: structural biology of marine polyketide synthasesPolyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthaseCharacterization of the lnmKLM genes unveiling key intermediates for β-alkylation in leinamycin biosynthesis.Top-down MS, a powerful complement to the high capabilities of proteolysis proteomics.Bifunctional acyltransferase/decarboxylase LnmK as the missing link for beta-alkylation in polyketide biosynthesis.Accessing natural product biosynthetic processes by mass spectrometry.Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrateNew tricks from ancient algae: natural products biosynthesis in marine cyanobacteria.The structural role of the carrier protein--active controller or passive carrier.Prospects for new antibiotics: a molecule-centered perspective.Progress challenges and opportunities for the re-engineering of trans-AT polyketide synthases.Polyketide biosynthesis in dinoflagellates: what makes it different?Insights into the chemical logic and enzymatic machinery of NRPS assembly lines.Biosynthesis of polyketides by trans-AT polyketide synthases.Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesisPyxipyrrolones: Structure Elucidation and Biosynthesis of Cytotoxic Myxobacterial Metabolites.Polyunsaturated fatty-acid-like trans-enoyl reductases utilized in polyketide biosynthesis.The Phormidolide Biosynthetic Gene Cluster: A trans-AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide.The AT₂ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS.
P2860
Q27648750-4CE31D79-A5E6-4034-9933-C8FE1E1DFE23Q27675905-CB733E0E-3E74-458D-9BF6-6114CFFADF82Q27680011-0BCD2641-C945-4AAA-AFCF-F187D3514A52Q28477732-37A6F360-4B34-40D5-A32D-CAFF1288E243Q33817435-4678E83E-ADFE-4584-8E07-1185C01DD1DEQ33924378-253C6953-34B6-4D95-BBB3-0C1D6D6AE690Q34052844-07EDF7F2-F66B-4245-9D4C-72DCFD267C10Q34096062-9E5D62BD-5DE4-4157-A18E-9799A7A2211BQ34122542-45C4CCC4-4B47-41EE-9B2E-5A87ECB9717CQ34267983-A6B684DD-4C69-4C1F-9F2F-23391B114606Q34346093-EB3AFC85-2524-4A3C-8309-811D6A018181Q34782058-AA3490CF-D02E-4145-912F-F6704B7876FDQ37004962-651D0821-5923-4858-A307-6D2F4F5252FDQ37230944-B5C5FE1F-C5B7-46EA-A50C-ECCECBB1CD47Q37244849-E82436B8-5656-4C3E-B5BA-E36557290467Q37264213-46AC15AD-BE24-4B8B-BABA-BD560D27A8E8Q37420999-07309861-1E93-4801-821E-8C26B61E683DQ38038812-C7581356-B7CB-4CC1-AC3D-E4F4DDB4047CQ38113689-EBA86DEF-B1A5-4279-AF70-9282A71FF109Q38189999-CC41D56B-55B2-4B13-BAE3-8B13A1A6316BQ38220326-93E4809F-C79A-4EF2-993A-09B1EF427E4FQ38547273-906D3D31-E89D-4BCD-8C95-2A4B6631B619Q38675125-F07FD888-5B82-49DE-ADFE-0CD7FD07D7B1Q39641894-8881399F-6D33-4136-B39B-32712DB4292EQ40182026-E806B844-097F-4A4E-BD04-C7C175C4A587Q41858950-F5DA5AB7-8E5D-4D2F-8E97-C170240554FDQ42764696-A3A16A43-689E-40BF-9A90-749B045D0D39Q44144019-CB98E4E8-C76F-44A7-A265-7F7720BC8DAF
P2860
Incorporation of nonmethyl branches by isoprenoid-like logic: multiple beta-alkylation events in the biosynthesis of myxovirescin A1.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Incorporation of nonmethyl bra ...... osynthesis of myxovirescin A1.
@en
type
label
Incorporation of nonmethyl bra ...... osynthesis of myxovirescin A1.
@en
prefLabel
Incorporation of nonmethyl bra ...... osynthesis of myxovirescin A1.
@en
P2093
P2860
P1476
Incorporation of nonmethyl bra ...... osynthesis of myxovirescin A1.
@en
P2093
Christopher T Calderone
Christopher T Walsh
David F Iwig
Neil L Kelleher
Pieter C Dorrestein
P2860
P304
P356
10.1016/J.CHEMBIOL.2007.06.008
P577
2007-07-01T00:00:00Z