Desmoglein endocytosis and desmosome disassembly are coordinated responses to pemphigus autoantibodies.
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Desmosomal cadherins are decreased in explanted arrhythmogenic right ventricular dysplasia/cardiomyopathy patient heartsNanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1βThe desmosomeAdherens junction turnover: regulating adhesion through cadherin endocytosis, degradation, and recyclingSynapse adhesion: a dynamic equilibrium conferring stability and flexibilityDesmosomes in acquired diseaseMechanistic basis of desmosome-targeted diseasesDesmosome assembly and disassembly are membrane raft-dependentLis1 is essential for cortical microtubule organization and desmosome stability in the epidermisPemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanismEGFR and ADAMs cooperate to regulate shedding and endocytic trafficking of the desmosomal cadherin desmoglein 2.Inhibition of Rho A activity causes pemphigus skin blistering.Peptides Targeting the Desmoglein 3 Adhesive Interface Prevent Autoantibody-induced Acantholysis in Pemphigus.Pathogenic epitopes of autoantibodies in pemphigus reside in the amino-terminal adhesive region of desmogleins which are unmasked by proteolytic processing of prosequence.Stat3 regulates desmoglein 3 transcription in epithelial keratinocytes.Antimitochondrial autoantibodies in pemphigus vulgaris: a missing link in disease pathophysiologyp38MAPK signaling and desmoglein-3 internalization are linked events in pemphigus acantholysis.Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies.Xenopus Kazrin interacts with ARVCF-catenin, spectrin and p190B RhoGAP, and modulates RhoA activity and epithelial integrity.Plakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: implications for exfoliative toxin-mediated skin blistering.Autoimmunity to desmocollin 3 in pemphigus vulgaris.Cleavage isn't everything: potential novel mechanisms of exfoliative toxin-mediated blistering.p38 MAPK activation is downstream of the loss of intercellular adhesion in pemphigus vulgaris.Signaling dependent and independent mechanisms in pemphigus vulgaris blister formationThe caspase pathway as a possible therapeutic target in experimental pemphigusStructure, function, and regulation of desmosomes.Pathogenic relevance of IgG and IgM antibodies against desmoglein 3 in blister formation in pemphigus vulgarisThe extent of desmoglein 3 depletion in pemphigus vulgaris is dependent on Ca(2+)-induced differentiation: a role in suprabasal epidermal skin splitting?Nanorobotic investigation identifies novel visual, structural and functional correlates of autoimmune pathology in a blistering skin disease model.Desmoglein-2: a novel regulator of apoptosis in the intestinal epithelium.Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma.Super-Resolution Microscopy Reveals Altered Desmosomal Protein Organization in Tissue from Patients with Pemphigus Vulgaris.Desmoglein autoimmunity in the pathogenesis of pemphigus.Significance of autoimmunity to non-desmoglein targets in pemphigus.Pemphigus antibody induced phosphorylation of keratinocyte proteins.Immunoadsorption in pemphigus.Pemphigus in the XXI century: new life to an old story.The desmosome and pemphigus.A pathophysiologic role for epidermal growth factor receptor in pemphigus acantholysisLoss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes
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P2860
Desmoglein endocytosis and desmosome disassembly are coordinated responses to pemphigus autoantibodies.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Desmoglein endocytosis and des ...... s to pemphigus autoantibodies.
@en
type
label
Desmoglein endocytosis and des ...... s to pemphigus autoantibodies.
@en
prefLabel
Desmoglein endocytosis and des ...... s to pemphigus autoantibodies.
@en
P2093
P2860
P356
P1476
Desmoglein endocytosis and des ...... s to pemphigus autoantibodies.
@en
P2093
Andrew P Kowalczyk
Cathárine C Calkins
Jean Marie Jennings
Kazuyuki Tsunoda
Shannon V Setzer
Susan Summers
P2860
P304
P356
10.1074/JBC.M512447200
P407
P577
2005-12-23T00:00:00Z