Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma. - Wikidata - awgldk - TriplyDB

Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma.

Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma.

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Stem Cell Hierarchy and Clonal Evolution in Acute Lymphoblastic Leukemia The emerging role of Twist proteins in hematopoietic cells and hematological malignancies Epstein-Barr virus and the origin of Hodgkin lymphoma Id2 intrinsically regulates lymphoid and erythroid development via interaction with different target proteins A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus Incomplete cytokinesis and re-fusion of small mononucleated Hodgkin cells lead to giant multinucleated Reed-Sternberg cells.Aberrant expression of ID2 protein and its correlation with EBV-LMP1 and P16(INK4A) in classical Hodgkin lymphoma in China.Three-dimensional culturing of the Hodgkin lymphoma cell-line L1236 induces a HL tissue-like gene expression pattern.Classification of lymphoid neoplasms: the microscope as a tool for disease discovery.Reciprocal t(9;22) ABL/BCR fusion proteins: leukemogenic potential and effects on B cell commitment.Lymphoma stem cells: enough evidence to support their existence?Hematopoiesis in steady-state versus stress: self-renewal, lineage fate choice, and the conversion of danger signals into cytokine signals in hematopoietic stem cells The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia.Clinical, molecular, and environmental risk factors for hodgkin lymphoma.Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma The molecular pathogenesis of Hodgkin lymphoma.Hodgkin lymphoma.E47 regulates hematopoietic stem cell proliferation and energetics but not myeloid lineage restriction.The B lineage transcription factor E2A regulates apoptosis in chronic lymphocytic leukemia (CLL) cells.Classical Hodgkin's lymphoma shows epigenetic features of abortive plasma cell differentiation.Myor/ABF-1 mRNA [corrected] Expression Marks Follicular Helper T Cells but Is Dispensable for Tfh Cell Differentiation and Function In Vivo.Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.Glioma-associated oncogene homologue 3, a hedgehog transcription factor, is highly expressed in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma.Aberrant expression of ID2, a suppressor of B-cell-specific gene expression, in Hodgkin's lymphoma.Aberrantly Expressed OTX Homeobox Genes Deregulate B-Cell Differentiation in Hodgkin Lymphoma.An auto-regulatory loop for EBV LMP2A involves activation of Notch.Aberrant expression of homeobox gene SIX1 in Hodgkin lymphoma.Histone acetylation and DNA demethylation of T cells result in an anaplastic large cell lymphoma-like phenotype.IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis Gene-expression of metastasized versus non-metastasized primary head and neck squamous cell carcinomas: a pathway-based analysis.Recent insights into the biology of Hodgkin lymphoma: unraveling the mysteries of the Reed-Sternberg cell.Contribution of the Epstein Barr virus to the molecular pathogenesis of Hodgkin lymphoma.Balance between Id and E proteins regulates myeloid-versus-lymphoid lineage decisions.MyoD and E-protein heterodimers switch rhabdomyosarcoma cells from an arrested myoblast phase to a differentiated state.Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma.Repression of TCF3/E2A contributes to Hodgkin lymphomagenesis.Pitfalls in diagnostic hematopathology -- Part II Epigenetic mechanisms regulating normal and malignant haematopoiesis: new therapeutic targets for clinical medicine.Molecular resolution of the B cell landscape.Transcriptional and epigenetic regulation of B cell development.

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Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma.

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Intrinsic inhibition of transc ...... c B cells in Hodgkin lymphoma.

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Intrinsic inhibition of transc ...... c B cells in Hodgkin lymphoma.

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Andreas Lietz

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Bernd Dörken

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Brigitte Wollert-Wulf

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Franziska Hummel

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Harald Stein

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Ioannis Anagnostopoulos

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Korinna Jöhrens

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Kurt Bommert

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Martin Janz

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Michael Hummel

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P2860

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

Characterization of ABF-1, a novel basic helix-loop-helix transcription factor expressed in activated B lymphocytes.

Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent

Id helix-loop-helix proteins antagonize pax transcription factor activity by inhibiting DNA binding

B-cell-specific DNA binding by an E47 homodimer

Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma

Inhibition of p300/CBP by early B-cell factor

A system for stable expression of short interfering RNAs in mammalian cells

Modulation of basic helix-loop-helix transcription complex formation by Id proteins during neuronal differentiation

Gradient of E2A activity in B-cell development.

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207-215

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10.1038/NI1285

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2

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7

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Franziska Jundt

Mikael Sigvardsson

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2005-12-20T00:00:00Z

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16369535

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