The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia. - Wikidata - awgldk - TriplyDB

The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia.

The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia.

http://www.wikidata.org/entity/Q34099472

about

Mutations, kataegis and translocations in B cells: understanding AID promiscuous activity Regulation of Aicda expression and AID activity The APOBEC3 family of retroelement restriction factors AID targeting: old mysteries and new challenges ABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1.SNP array analysis of tyrosine kinase inhibitor-resistant chronic myeloid leukemia identifies heterogeneous secondary genomic alterations.In vivo and in vitro studies suggest a possible involvement of HPV infection in the early stage of breast carcinogenesis via APOBEC3B induction.Generation and repair of AID-initiated DNA lesions in B lymphocytes.Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes Selective induction of DNA repair pathways in human B cells activated by CD4+ T cells Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells.Chronic myeloid leukemia: mechanisms of blastic transformation Activation-induced cytidine deaminase accelerates clonal evolution in BCR-ABL1-driven B-cell lineage acute lymphoblastic leukemia.Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90.The Ph-positive and Ph-negative myeloproliferative neoplasms: some topical pre-clinical and clinical issues.Complex regulation and function of activation-induced cytidine deaminase.Histone demethylase RBP2 decreases miR-21 in blast crisis of chronic myeloid leukemia.Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia.BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia.Bmi1 reprograms CML B-lymphoid progenitors to become B-ALL-initiating cells.HSP90 inhibitors decrease AID levels and activity in mice and in human cells.AID/APOBEC-network reconstruction identifies pathways associated with survival in ovarian cancer.Mechanisms of Yin Yang 1 in oncogenesis: the importance of indirect effects.Environment-mediated drug resistance in Bcr/Abl-positive acute lymphoblastic leukemia AIDing cancer treatment: Reducing AID activity via HSP90 inhibition Activation-induced Cytidine Deaminase in B Cell Immunity and Cancers.CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia.APOBEC3A damages the cellular genome during DNA replication Nucleic acid determinants for selective deamination of DNA over RNA by activation-induced deaminase.APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.B cell-specific deficiencies in mTOR limit humoral immune responses.AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine.Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination Imatinib induces H2AX phosphorylation and apoptosis in chronic myelogenous leukemia cells in vitro via caspase-3/Mst1 pathway.A Novel Regulator of Activation-Induced Cytidine Deaminase/APOBECs in Immunity and Cancer: Schrödinger's CATalytic Pocket.BCR-ABL: a multi-faceted promoter of DNA mutation in chronic myelogeneous leukemia.The curious chemical biology of cytosine: deamination, methylation, and oxidation as modulators of genomic potential.Genetic mechanisms of chronic myeloid leukemia blastic transformation.The role of activation-induced deaminase in antibody diversification and genomic instability.Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells

P2860

Q26768663-6DD461E0-7BE3-460B-A0F3-5DB5A7624163 Q26853622-92036BE3-FD78-4E68-99C5-D086E74E6642 Q26862780-9A9ED251-A32B-4A0A-84FD-416698173512 Q28265992-25E7B977-AB6D-44CD-AD2C-17136D79A283 Q30155948-7E420679-C32D-4A5B-9AB5-F1E81482F657 Q33517413-76F61518-8FFD-4EE4-8761-8E3D8782CC49 Q33654853-51E1E531-3DF7-4068-8D84-C95E72DA9C73 Q33690522-9986D88F-FD53-4031-8280-05D9A770B57C Q33757410-32A5095A-CFE3-4BC5-880A-0C865271B999 Q33778759-0F090834-F0B3-415B-8D03-8C4B503FE5CD Q33959401-0FF1DE9B-4CFB-46D9-A3C8-101F066F9510 Q33968037-0C248DB6-D77E-44C5-BB1E-48D93604B0C5 Q34168766-A0381336-9491-4A5E-A3DF-ADAB52700155 Q34340626-335EFEE1-65FA-47FF-AD34-E7DA786B6B3C Q34750582-5E2B0DFE-A520-48CA-89F6-7F0EBDF33840 Q34958445-63275EC5-84DF-4D5C-9622-0BBB29179B77 Q35176062-54F52A82-663E-4E39-99AD-539C711BB190 Q35182716-E9C82816-1354-445A-B76A-320AB08D8AE4 Q35441406-367B92CF-718E-4B25-AA94-1D940E9F455B Q35669231-B48EB773-1AC3-4FAF-9A44-E4511686F23E Q35952172-3CA03F21-E0BB-4F74-AFAC-09608CA7651E Q36104522-1DCA2F2B-6383-4D10-BE9D-151800BB651C Q36157946-8B8ED203-C168-4E64-8A03-9D0F948459C6 Q36194829-C392BC8E-901F-4AD6-A983-910A071600B0 Q36367487-18B41995-9A7C-42EC-8301-253CCE626C75 Q36592764-E93633C6-6562-4C91-A9B1-5A748015D951 Q36891005-1A5073A9-EC9F-48AF-BB99-3EB5BDC677BF Q36956935-CD2D12E1-7315-4484-B1BD-9A16BFE33D74 Q37143544-313DD88D-EAFB-4FE6-8E5E-31883008B16A Q37402303-CA4BE320-066C-41B7-B873-7AA5F06AA666 Q37532105-21FD8478-A7FA-4C12-BDAC-DDC055B5B7BD Q37649663-16608C2F-AF03-4F85-9CD0-CC5481711E98 Q37659903-0E2FA2E0-04BD-407C-BC8B-979258427BCE Q37729966-9120B356-CB48-4308-A9B9-3E1CEB642149 Q37739072-B12AA39F-4EDA-48A6-BC5B-32A754F4A45F Q37743173-FF934BDC-E0FF-40A4-ACA9-708B968F6C01 Q37946460-916BB7DA-2F0E-48E2-8CA3-4F34B41EEB8C Q37983490-3E622DBB-4BCA-4F62-92DC-39C5365BBAE0 Q38041514-3A0321C3-401E-4652-A7BB-92CF5CB1A866 Q38716411-E5179336-7A32-4DE2-A84A-425FFDFB1508

P2860

The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia.

http://www.wikidata.org/entity/Q34099472

description

2009 nî lūn-bûn

@nan

2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

The B cell mutator AID promote ...... e in chronic myeloid leukemia.

@ast

The B cell mutator AID promote ...... e in chronic myeloid leukemia.

@en

The B cell mutator AID promote ...... e in chronic myeloid leukemia.

@nl

type

label

The B cell mutator AID promote ...... e in chronic myeloid leukemia.

@ast

The B cell mutator AID promote ...... e in chronic myeloid leukemia.

@en

The B cell mutator AID promote ...... e in chronic myeloid leukemia.

@nl

prefLabel

The B cell mutator AID promote ...... e in chronic myeloid leukemia.

@ast

The B cell mutator AID promote ...... e in chronic myeloid leukemia.

@en

The B cell mutator AID promote ...... e in chronic myeloid leukemia.

@nl

P1433

Q34099472-854ACDE8-4F41-4E9B-A151-B1A724948C2E

P1476

Q34099472-9B311F1C-C3C9-4AA4-B5A4-D3D5921DDF3F

P2093

Q34099472-017B69BD-5D3A-4CF6-A867-0B61358E25F6

Q34099472-08456FED-A158-405C-8793-182748A604B0

Q34099472-199B83FE-6EB3-4152-BB1B-9CDC6B94FBAC

Q34099472-1D18073A-7306-494B-894F-BB80B6B5A7AE

Q34099472-300D1FD0-BDAD-4D2F-9B08-CA6A582F3681

Q34099472-30CA376F-6011-4406-9A3F-4D728D66908D

Q34099472-4128CC85-CCAA-4FCB-BD05-2E1DE91ADD39

Q34099472-4B8E299D-ABED-4811-82F1-9FEE20A3F97A

Q34099472-6E733BB2-ACA5-47CA-BBEB-8863911800B9

Q34099472-A225C300-C05E-480E-99AD-0FAF4DD6C269

P2860

Q34099472-00645DE1-4A9D-480C-9173-1F4EA270BDD6

Q34099472-0271FCB5-0FB1-4609-8827-F5BEB86B4816

Q34099472-06006727-5C1F-4BFD-AE18-2361330F0BCC

Q34099472-065C1449-F47F-4420-ACBA-50B3B778AE5D

Q34099472-06B28912-147F-4F4F-8860-23BD4C74A75B

Q34099472-0BDEC62A-AF41-406C-A534-838900E7F7D8

Q34099472-0F626B42-0BBB-4945-BC46-2201D2D09A65

Q34099472-12C2DB1A-40D0-467C-8B47-D7C0A68AE0B2

Q34099472-17F09CB9-4E81-419F-A2AC-BB76FC979708

Q34099472-189967E5-82B9-45C1-8920-A0EE50AB888F

P304

Q34099472-9D09F770-848B-4185-91FA-C5E10799F41D

P31

Q34099472-53D7B66D-9A25-4BFF-BDBB-51D914222B7A

P356

Q34099472-3136B4FF-D8DD-4B7B-8350-48C43CB0B8C5

P433

Q34099472-0DBF309B-186F-4208-B705-E84415CB8FB6

P478

Q34099472-C71E95F8-58E5-489A-BCE6-5A84DCDAAA90

P50

Q34099472-40B856A7-A929-4BD0-891E-1FE156F3D36F

Q34099472-4FC68D38-D311-486D-8762-33E5129656EB

Q34099472-6D568265-838D-4A0C-A721-97955338B5C9

Q34099472-C2734A45-16DD-4AD0-A8FD-6025DD02060A

P577

Q34099472-105805DB-CBA0-41F1-B2E4-103E2EEEB1AD

P5875

Q34099472-CA0B1F78-7BD9-4FB8-8498-E8A02602A82E

P698

Q34099472-9B8CE3C1-A54D-4DBF-83CB-459B02EAF6BE

P921

Q34099472-B9CC2F56-B5B5-494F-A9B6-148A85AF93DD

Q34099472-E8841D24-3301-4CA3-A6E2-83FFEFAC742B

P932

Q34099472-137F24B6-6B9B-4487-A9D4-B1F55D87F91D

P356

J.CCR.2009.07.030

P1433

P1476

The B cell mutator AID promote ...... e in chronic myeloid leukemia.

@en

P2093

Cihangir Duy

http://www.w3.org/2001/XMLSchema#string

Gregor von Levetzow

http://www.w3.org/2001/XMLSchema#string

Hassan Jumaa

http://www.w3.org/2001/XMLSchema#string

John Groffen

http://www.w3.org/2001/XMLSchema#string

Lars Klemm

http://www.w3.org/2001/XMLSchema#string

Markus Müschen

http://www.w3.org/2001/XMLSchema#string

Michael R Lieber

http://www.w3.org/2001/XMLSchema#string

Nadine Henke

http://www.w3.org/2001/XMLSchema#string

Nora Heisterkamp

http://www.w3.org/2001/XMLSchema#string

Rafael Casellas

http://www.w3.org/2001/XMLSchema#string

P2860

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation

MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

P304

232-245

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.CCR.2009.07.030

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

16

http://www.w3.org/2001/XMLSchema#string

P50

Markus Müschen

Ilaria Iacobucci

Giovanni Martinelli

Niklas Feldhahn

P577

2009-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

26791794

http://www.w3.org/2001/XMLSchema#string

P698

19732723

http://www.w3.org/2001/XMLSchema#string

P921

chronic myeloid leukemia

P932

2931825

http://www.w3.org/2001/XMLSchema#string