Regulation of de novo purine biosynthesis by methenyltetrahydrofolate synthetase in neuroblastoma.
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Mthfs is an Essential Gene in Mice and a Component of the PurinosomeBioinformatic and genetic association analysis of microRNA target sites in one-carbon metabolism genesSHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesisThe structure of Enterococcus faecalis thymidylate synthase provides clues about folate bacterial metabolismPhase 2 trial of pemetrexed in children and adolescents with refractory solid tumors: a Children's Oncology Group study.Phenotypic landscape of a bacterial cellShmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice.Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apc(min)-mediated intestinal cancer risk.Bacterial conversion of folinic acid is required for antifolate resistance.Human mutations in methylenetetrahydrofolate dehydrogenase 1 impair nuclear de novo thymidylate biosynthesis.High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice.Insights into metabolic mechanisms underlying folate-responsive neural tube defects: a minireview.Nuclear localization of de novo thymidylate biosynthesis pathway is required to prevent uracil accumulation in DNAFolate network genetic variation predicts cardiovascular disease risk in non-Hispanic white malesExpression of Folate Pathway Genes in Stage III Colorectal Cancer Correlates with Recurrence Status Following Adjuvant Bolus 5-FU-Based Chemotherapy.Trafficking of intracellular folates.Alcohol Dehydrogenase 5 Is a Source of Formate for De Novo Purine Biosynthesis in HepG2 Cells.Regulation of folate-mediated one-carbon metabolism by 10-formyltetrahydrofolate dehydrogenase.Characterization and Interrelations of One-Carbon Metabolites in Tissues, Erythrocytes, and Plasma in Mice with Dietary Induced Folate Deficiency.A liquid chromatography-tandem mass spectrometric method for quantitative determination of native 5-methyltetrahydrofolate and its polyglutamyl derivatives in raw vegetables.5,10-Methenyltetrahydrofolate synthetase activity is increased in tumors and modifies the efficacy of antipurine LY309887.Inhibition of 5,10-methenyltetrahydrofolate synthetase.Folate rescues vitamin B12 depletion-induced inhibition of nuclear thymidylate biosynthesis and genome instability.Histidine catabolism is a major determinant of methotrexate sensitivity
P2860
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P2860
Regulation of de novo purine biosynthesis by methenyltetrahydrofolate synthetase in neuroblastoma.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Regulation of de novo purine b ...... e synthetase in neuroblastoma.
@en
type
label
Regulation of de novo purine b ...... e synthetase in neuroblastoma.
@en
prefLabel
Regulation of de novo purine b ...... e synthetase in neuroblastoma.
@en
P356
P1476
Regulation of de novo purine b ...... te synthetase in neuroblastoma
@en
P2093
Doletha M E Szebenyi
Patrick J Stover
P304
P356
10.1074/JBC.M510624200
P407
P577
2005-12-19T00:00:00Z