Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesis.
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Picornavirus genome replication: roles of precursor proteins and rate-limiting steps in oriI-dependent VPg uridylylationThe crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerasesPoliovirus cis-acting replication element-dependent VPg Uridylylation lowers the Km of the initiating nucleoside triphosphate for viral RNA replicationCis-acting RNA elements in human and animal plus-strand RNA virusesHuman rhinovirus type 14 gain-of-function mutants for oriI utilization define residues of 3C(D) and 3Dpol that contribute to assembly and stability of the picornavirus VPg uridylylation complexPicornavirus RNA polyadenylation by 3D(pol), the viral RNA-dependent RNA polymerasePolyadenylation of genomic RNA and initiation of antigenomic RNA in a positive-strand RNA virus are controlled by the same cis-elementThe capsid-coding region hairpin element (cHP) is a critical determinant of dengue virus and West Nile virus RNA synthesisToward genetics-based virus taxonomy: comparative analysis of a genetics-based classification and the taxonomy of picornavirusesScreening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2CNew complete genome sequences of human rhinoviruses shed light on their phylogeny and genomic features.An RNA element at the 5'-end of the poliovirus genome functions as a general promoter for RNA synthesis.Cytoplasmic viral RNA-dependent RNA polymerase disrupts the intracellular splicing machinery by entering the nucleus and interfering with Prp8Characterization of attenuated coxsackievirus B3 strains and prospects of their application as live-attenuated vaccines.Major alteration in coxsackievirus B3 genomic RNA structure distinguishes a virulent strain from an avirulent strain.Non-template functions of viral RNA in picornavirus replication.Characterization of protein-protein interactions critical for poliovirus replication: analysis of 3AB and VPg binding to the RNA-dependent RNA polymerase.Tyrosine 3 of poliovirus terminal peptide VPg(3B) has an essential function in RNA replication in the context of its precursor protein, 3AB.Amiloride inhibits the initiation of Coxsackievirus and poliovirus RNA replication by inhibiting VPg uridylylation.Picornavirus genome replication: assembly and organization of the VPg uridylylation ribonucleoprotein (initiation) complex.Mutational Disruption of cis-Acting Replication Element 2C in Coxsackievirus B3 Leads to 5'-Terminal Genomic Deletions.Enterovirus 71 VPg uridylation uses a two-molecular mechanism of 3D polymerase.Improved crystallization of the coxsackievirus B3 RNA-dependent RNA polymerasePoly(rC) binding proteins and the 5' cloverleaf of uncapped poliovirus mRNA function during de novo assembly of polysomesThe cis-acting replication elements define human enterovirus and rhinovirus species.Antiviral activity of micafungin against enterovirus 71.Cis-active RNA elements (CREs) and picornavirus RNA replication5-fluorouracil in lethal mutagenesis of foot-and-mouth disease virus.Picornavirus genome replication. Identification of the surface of the poliovirus (PV) 3C dimer that interacts with PV 3Dpol during VPg uridylylation and construction of a structural model for the PV 3C2-3Dpol complexMembrane topography of the hydrophobic anchor sequence of poliovirus 3A and 3AB proteins and the functional effect of 3A/3AB membrane association upon RNA replication.Initiation of protein-primed picornavirus RNA synthesis.Amiloride is a competitive inhibitor of coxsackievirus B3 RNA polymerase.Role of RNA structure and RNA binding activity of foot-and-mouth disease virus 3C protein in VPg uridylylation and virus replicationStructure-function analysis of the coxsackievirus protein 3A: identification of residues important for dimerization, viral rna replication, and transport inhibition.Azole resistance profile of amino acid changes in Aspergillus fumigatus CYP51A based on protein homology modeling.Cardiac fibroblasts aggravate viral myocarditis: cell specific coxsackievirus B3 replication.Amiloride derivatives inhibit coxsackievirus B3 RNA replication.Conversion of VPg into VPgpUpUOH before and during poliovirus negative-strand RNA synthesis.Fully automated sequential solid phase approach towards viral RNA-nucleopeptides.Gemcitabine, a broad-spectrum antiviral drug, suppresses enterovirus infections through innate immunity induced by the inhibition of pyrimidine biosynthesis and nucleotide depletion.
P2860
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P2860
Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesis.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Structural and functional char ...... positive-strand RNA synthesis.
@en
type
label
Structural and functional char ...... positive-strand RNA synthesis.
@en
prefLabel
Structural and functional char ...... positive-strand RNA synthesis.
@en
P2093
P50
P356
P1476
Structural and functional char ...... positive-strand RNA synthesis.
@en
P2093
Aniko Paul
Christian Castro
Dorothee A Vogt
Judith Kuijpers
Mark J M van Ooij
Raul Andino
Willem J G Melchers
P304
P356
10.1099/VIR.0.81297-0
P407
P577
2006-01-01T00:00:00Z