Gene transfer into the rat renal glomerulus via a mesangial cell vector: site-specific delivery, in situ amplification, and sustained expression of an exogenous gene in vivo.
about
Aberrant, differential and bidirectional regulation of the unfolded protein response towards cell survival by 3'-deoxyadenosineTranscriptional induction of mitogen-activated protein kinase phosphatase 1 by retinoids. Selective roles of nuclear receptors and contribution to the antiapoptotic effectmTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathwayER stress depresses NF-kappaB activation in mesangial cells through preferential induction of C/EBP betaGene therapy for kidney disease.Macrophage growth factors introduced into the kidney initiate renal injury.Creation of an In vivo cytosensor using engineered mesangial cells. Automatic sensing of glomerular inflammation controls transgene activity.Creation of a reversible on/off system for site-specific in vivo control of exogenous gene activity in the renal glomerulus.Profiling of functional phosphodiesterase in mesangial cells using a CRE-SEAP-based reporting system.Blockade of Smad signaling by 3'-deoxyadenosine: a mechanism for its anti-fibrotic potential.Suppression of cytokine responses by indomethacin in podocytes: a mechanism through induction of unfolded protein response.Real-time detection and continuous monitoring of ER stress in vitro and in vivo by ES-TRAP: evidence for systemic, transient ER stress during endotoxemia.Enhancement of NF-kappaB activity by resveratrol in cytokine-exposed mesangial cells.Continuous, noninvasive monitoring of local microscopic inflammation using a genetically engineered cell-based biosensor.Irsogladine maleate potentiates the effects of nitric oxide on activation of cAMP signalling pathways and suppression of mesangial cell mitogenesis.Selective abrogation of BiP/GRP78 blunts activation of NF-κB through the ATF6 branch of the UPR: involvement of C/EBPβ and mTOR-dependent dephosphorylation of Akt.Spontaneous shift in transcriptional profile of explanted glomeruli via activation of the MAP kinase family.Selective roles of retinoic acid receptor and retinoid x receptor in the suppression of apoptosis by all-trans-retinoic acid.Spontaneous activation of the NF-kappaB signaling pathway in isolated normal glomeruli.Selective sensitization to tumor necrosis factor-alpha-induced apoptosis by blockade of NF-kappaB in primary glomerular mesangial cells.
P2860
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P2860
Gene transfer into the rat renal glomerulus via a mesangial cell vector: site-specific delivery, in situ amplification, and sustained expression of an exogenous gene in vivo.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Gene transfer into the rat ren ...... of an exogenous gene in vivo.
@en
type
label
Gene transfer into the rat ren ...... of an exogenous gene in vivo.
@en
prefLabel
Gene transfer into the rat ren ...... of an exogenous gene in vivo.
@en
P2093
P2860
P356
P1476
Gene transfer into the rat ren ...... n of an exogenous gene in vivo
@en
P2093
P2860
P304
P356
10.1172/JCI117361
P407
P577
1994-08-01T00:00:00Z