Cisplatin-induced hepatotoxicity is enhanced by elevated expression of cytochrome P450 2E1.
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Standardizing adverse drug event reporting dataContributions of human enzymes in carcinogen metabolismModulatory influence of Acacia hydaspica R. Parker ethyl acetate extract against cisplatin inveigled hepatic injury and dyslipidemia in rats.Hepatitis B virus X protein enhances cisplatin-induced hepatotoxicity via a mechanism involving degradation of Mcl-1.Protective effects of pine bark extract against cisplatin-induced hepatotoxicity and oxidative stress in ratsAlteration in the expression of cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the liver of mouse induced by microcystin-LR.Absence of cytochrome P450 2A5 enhances alcohol-induced liver injury in mice.In-depth identification of pathways related to cisplatin-induced hepatotoxicity through an integrative method based on an informatics-assisted label-free protein quantitation and microarray gene expression approach.Hepatotoxicity and pharmacokinetics of cisplatin in combination therapy with a traditional Chinese medicine compound of Zengmian Yiliu granules in ICR mice and SKOV-3-bearing nude miceGenome-wide Association Study on Platinum-induced Hepatotoxicity in Non-Small Cell Lung Cancer Patients.Tangeretin Alleviates Cisplatin-Induced Acute Hepatic Injury in Rats: Targeting MAPKs and Apoptosis.Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathwayPyrazole induced oxidative liver injury independent of CYP2E1/2A5 induction due to Nrf2 deficiencyExperimental nonalcoholic fatty liver disease in mice leads to cytochrome p450 2a5 upregulation through nuclear factor erythroid 2-like 2 translocationA 7-day profile of oxidative stress and antioxidant status in patients with acute liver failureThe potential role of Azadirachta indica treatment on cisplatin-induced hepatotoxicity and oxidative stress in female rats.Assessment of anti-mutagenic, anti-histopathologic and antioxidant capacities of Egyptian bee pollen and propolis extracts.Oxidative stress induced in nurses by exposure to preparation and handling of antineoplastic drugs in Mexican hospitals: a multicentric study.Hepatoprotective effect of Zataria Multiflora Boisson cisplatin-induced oxidative stress in male ratA review of drug-induced liver injury databases.Expression of stress-dependent genes in hepatocytes spheroids after cisplatin treatment.Liposomes loaded with a dirhenium compound and cisplatin: preparation, properties and improved in vivo anticancer activity.Genome-Wide Association Studies for Idiosyncratic Drug-Induced Hepatotoxicity: Looking Back-Looking Forward to Next-Generation Innovation.HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved.Involvement of cytochrome P450 in cisplatin treatment: implications for toxicity.The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin.Biochemical changes associated with ascorbic acid-cisplatin combination therapeutic efficacy and protective effect on cisplatin-induced toxicity in tumor-bearing mice.Mitochondrial/lysosomal toxic cross-talk plays a key role in cisplatin nephrotoxicity.Cisplatin- and dietary ascorbic acid-mediated changes in the mitochondria of Dalton's lymphoma-bearing mice.4-Hydroxynonenal induces mitochondrial-mediated apoptosis and oxidative stress in SH-SY5Y human neuronal cells.The antitumor effects of tetrodotoxin and/or doxorubicin on Ehrlich ascites carcinoma-bearing female mice.Toxicological Implications of Mitochondrial Localization of CYP2E1.Severe acute toxicity following gemcitabine administration: A report of four cases with cytidine deaminase polymorphisms evaluation.L-Buthionine (S,R) sulfoximine depletes hepatic glutathione but protects against ethanol-induced liver injury.Cytochrome P450s And Alcoholic Liver Disease.The Beneficial Effects of Fish Oil Following Cisplatin-Induced Oxidative and Histological Damage in Liver of Rats.
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P2860
Cisplatin-induced hepatotoxicity is enhanced by elevated expression of cytochrome P450 2E1.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Cisplatin-induced hepatotoxici ...... ession of cytochrome P450 2E1.
@en
type
label
Cisplatin-induced hepatotoxici ...... ession of cytochrome P450 2E1.
@en
prefLabel
Cisplatin-induced hepatotoxici ...... ession of cytochrome P450 2E1.
@en
P2860
P356
P1476
Cisplatin-induced hepatotoxici ...... ession of cytochrome P450 2E1.
@en
P2093
Arthur I Cederbaum
P2860
P304
P356
10.1093/TOXSCI/KFJ031
P577
2005-10-26T00:00:00Z