Mutations of beta-catenin in adrenocortical tumors: activation of the Wnt signaling pathway is a frequent event in both benign and malignant adrenocortical tumors.
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ARMC5 mutations in macronodular adrenal hyperplasia with Cushing's syndromeMouse Models Recapitulating Human Adrenocortical Tumors: What Is Lacking?Molecular genetics of adrenocortical tumor formation and potential pharmacologic targetsToying with fate: Redirecting the differentiation of adrenocortical progenitor cells into gonadal-like tissueDiagnostic and prognostic features in adrenocortical carcinoma: a single institution case series and review of the literatureAnalysis of the role of Igf2 in adrenal tumour development in transgenic mouse modelsUpregulated JAG1 enhances cell proliferation in adrenocortical carcinomaWhole-exome sequencing characterizes the landscape of somatic mutations and copy number alterations in adrenocortical carcinoma.Review paper: origin and molecular pathology of adrenocortical neoplasmsPhysiological and Pathological Roles in Human Adrenal of the Glomeruli-Defining Matrix Protein NPNT (Nephronectin).Extracellular activation of Wnt signaling through epigenetic dysregulation of Wnt inhibitory factor-1 (Wif-1) is associated with pathogenesis of adrenocortical tumor.The activating TERT promoter mutation C228T is recurrent in subsets of adrenal tumorsRecurrent activating mutation in PRKACA in cortisol-producing adrenal tumorsRARRES2 functions as a tumor suppressor by promoting β-catenin phosphorylation/degradation and inhibiting p38 phosphorylation in adrenocortical carcinoma.Regulation of steroidogenesis in a primary pigmented nodular adrenocortical disease-associated adenoma leading to virilization and subclinical Cushing's syndrome.Inhibin alpha-subunit (INHA) expression in adrenocortical cancer is linked to genetic and epigenetic INHA promoter variation.Knockdown of SF-1 and RNF31 affects components of steroidogenesis, TGFβ, and Wnt/β-catenin signaling in adrenocortical carcinoma cells.Silencing mutated β-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line H295R.How does cAMP/protein kinase A signaling lead to tumors in the adrenal cortex and other tissues?A comparative proteomic study identified calreticulin and prohibitin up-regulated in adrenocortical carcinomas.Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma.Targeting β-catenin signaling for therapeutic intervention in MEN1-deficient pancreatic neuroendocrine tumours.Single nucleotide polymorphism array profiling of adrenocortical tumors--evidence for an adenoma carcinoma sequence?Emerging therapy for adrenocortical carcinoma.Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumorsDetection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease (PPNAD).Therapy of adrenocortical cancer: present and future.Current and emerging therapies for advanced adrenocortical carcinoma.Adrenocortical carcinoma: clinical outcomes and prognosis of 330 patients at a tertiary care centerAdrenocortical neoplasia: evolving concepts in tumorigenesis with an emphasis on adrenal cortical carcinoma variants.Molecular and Cellular Mechanisms of Aldosterone Producing Adenoma DevelopmentAdrenocortical stem and progenitor cells: implications for adrenocortical carcinomaAnimal models of adrenocortical tumorigenesisLoss of β-catenin in adrenocortical cancer cells causes growth inhibition and reversal of epithelial-to-mesenchymal transitionDevelopment of adrenal cortex zonation.Combined transcriptome studies identify AFF3 as a mediator of the oncogenic effects of β-catenin in adrenocortical carcinoma.Pathway Implications of Aberrant Global Methylation in Adrenocortical CancerGenomic and immunohistochemical analysis in human adrenal cortical neoplasia reveal beta-catenin mutations as potential prognostic biomarkerAdrenocortical stem and progenitor cells: unifying model of two proposed origins.Pregnancy, Primary Aldosteronism, and Adrenal CTNNB1 Mutations.
P2860
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P2860
Mutations of beta-catenin in adrenocortical tumors: activation of the Wnt signaling pathway is a frequent event in both benign and malignant adrenocortical tumors.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Mutations of beta-catenin in a ...... lignant adrenocortical tumors.
@en
type
label
Mutations of beta-catenin in a ...... lignant adrenocortical tumors.
@en
prefLabel
Mutations of beta-catenin in a ...... lignant adrenocortical tumors.
@en
P2093
P1433
P1476
Mutations of beta-catenin in a ...... lignant adrenocortical tumors.
@en
P2093
Anne-Marie Hagneré
Catherine Cavard
Christine Gicquel
Christine Perret
Eric Jullian
Fernande René-Corail
Frédérique Tissier
Gwladys Fumey
Karine Perlemoine
Lionel Groussin
P304
P356
10.1158/0008-5472.CAN-05-0593
P407
P577
2005-09-01T00:00:00Z