Coordinate control and selective expression of the full complement of replication-dependent histone H4 genes in normal and cancer cells.
about
The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motifCDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-PThe histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cyclesThe architectural organization of human stem cell cycle regulatory machineryThe SR protein B52/SRp55 is required for DNA topoisomerase I recruitment to chromatin, mRNA release and transcription shutdown.Fidelity of histone gene regulation is obligatory for genome replication and stability.Topoisomerase I suppresses genomic instability by preventing interference between replication and transcriptionMatrix-assisted laser desorption/ionization mass spectrometry reveals decreased calcylcin expression in small cell lung cancer.The subnuclear organization of histone gene regulatory proteins and 3' end processing factors of normal somatic and embryonic stem cells is compromised in selected human cancer cell types.Transcriptional activation of the histone nuclear factor P (HiNF-P) gene by HiNF-P and its cyclin E/CDK2 responsive co-factor p220NPAT defines a novel autoregulatory loop at the G1/S phase transition.A multiprotein occupancy map of the mRNP on the 3' end of histone mRNAs.p53 checkpoint ablation exacerbates the phenotype of Hinfp dependent histone H4 deficiency.Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle.The abbreviated pluripotent cell cycle.Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cellsHistone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells.Tgfbr2 is required for development of the skull vault.Transcription-replication encounters, consequences and genomic instability.Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development.Multilayered chromatin analysis reveals E2f, Smad and Zfx as transcriptional regulators of histones.The histone gene transcription factor HiNF-P stabilizes its cell cycle regulatory co-activator p220NPAT.Maternal expression and early induction of histone gene transcription factor Hinfp sustains development in pre-implantation embryos.
P2860
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P2860
Coordinate control and selective expression of the full complement of replication-dependent histone H4 genes in normal and cancer cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Coordinate control and selecti ...... es in normal and cancer cells.
@en
type
label
Coordinate control and selecti ...... es in normal and cancer cells.
@en
prefLabel
Coordinate control and selecti ...... es in normal and cancer cells.
@en
P2093
P2860
P356
P1476
Coordinate control and selecti ...... es in normal and cancer cells.
@en
P2093
Andre J van Wijnen
Corey D Braastad
Cornelia Hampe
Detlef Doenecke
Gary S Stein
Janet L Stein
Partha Mitra
Werner Albig
William F Holmes
P2860
P304
37400-37407
P356
10.1074/JBC.M506995200
P407
P577
2005-08-29T00:00:00Z