mTOR-dependent suppression of protein phosphatase 2A is critical for phospholipase D survival signals in human breast cancer cells.
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Myc stabilization in response to estrogen and phospholipase D in MCF-7 breast cancer cellsDesign, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitorRapamycin improves lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome (ALPS)Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.Frontier of epilepsy research - mTOR signaling pathway.Paxillin phosphorylation and complexing with Erk and FAK are regulated by PLD activity in MDA-MB-231 cellsDiabetes diminishes phosphatidic acid in the retina: a putative mediator for reduced mTOR signaling and increased neuronal cell death.Investigating mammalian target of rapamycin inhibitors for their anticancer properties.Phospholipase D provides a survival signal in human cancer cells with activated H-Ras or K-Ras.The B56γ3 regulatory subunit-containing protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phospho-Thr157 of p27KIP1.The potential for phospholipase D as a new therapeutic target.Protein phosphatase 2A and DNA-dependent protein kinase are involved in mediating rapamycin-induced Akt phosphorylation.Phosphatidic acid and lipid-sensing by mTORPhosphatidic acid signaling to mTOR: signals for the survival of human cancer cells.Honokiol suppresses survival signals mediated by Ras-dependent phospholipase D activity in human cancer cells.Phosphatidic acid, phospholipase D and tumorigenesis.New insights into p53 signaling and cancer cell response to DNA damage: implications for cancer therapy.Comparisons between murine polyomavirus and Simian virus 40 show significant differences in small T antigen function.AQP3 small interfering RNA and PLD2 small interfering RNA inhibit the proliferation and promote the apoptosis of squamous cell carcinomaTranslational up-regulation and high-level protein expression from plasmid vectors by mTOR activation via different pathways in PC3 and 293T cellsHIF alpha expression in VHL-deficient renal cancer cells is dependent on phospholipase D.Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D.Temsirolimus enhances the efficacy of cetuximab in colon cancer through a CIP2A-dependent mechanism.Dynamics of elongation factor 2 kinase regulation in cortical neurons in response to synaptic activity.Effect of gamma-synuclein silencing on apoptotic pathways in retinal ganglion cells.Elevated phospholipase D activity in androgen-insensitive prostate cancer cells promotes both survival and metastatic phenotypes.
P2860
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P2860
mTOR-dependent suppression of protein phosphatase 2A is critical for phospholipase D survival signals in human breast cancer cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
mTOR-dependent suppression of ...... in human breast cancer cells.
@en
type
label
mTOR-dependent suppression of ...... in human breast cancer cells.
@en
prefLabel
mTOR-dependent suppression of ...... in human breast cancer cells.
@en
P2093
P2860
P356
P1476
mTOR-dependent suppression of ...... in human breast cancer cells.
@en
P2093
David A Foster
Rafal M Pielak
Stefan Knirr
Vanessa Rodrik
Yang Zheng
P2860
P304
35829-35835
P356
10.1074/JBC.M504192200
P407
P577
2005-08-18T00:00:00Z