The propeptide region of clotting factor IX is a signal for a vitamin K dependent carboxylase: evidence from protein engineering of amino acid -4.
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Modification of the N-terminus of human factor IX by defective propeptide cleavage or acetylation results in a destabilized calcium-induced conformation: effects on phospholipid binding and activation by factor XIaThe role of beta-hydroxyaspartate and adjacent carboxylate residues in the first EGF domain of human factor IXFunctional expression of the human coagulation factor IX using heterologous signal peptide and propeptide sequences in mammalian cell line.Expression of biologically active human clotting factor IX in Drosophila S2 cells: γ-carboxylation of a human vitamin K-dependent protein by the insect enzyme.Defective propeptide processing and abnormal activation underlie the molecular pathology of factor IX Troed-y-Rhiw.Effect of propeptide amino acid substitution in γ-carboxylation, activity and expression of recombinant human coagulation factor IX.
P2860
The propeptide region of clotting factor IX is a signal for a vitamin K dependent carboxylase: evidence from protein engineering of amino acid -4.
description
1987 nî lūn-bûn
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1987年の論文
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1987年学术文章
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1987年学术文章
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1987年学术文章
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1987年学术文章
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1987年学术文章
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1987年學術文章
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1987年學術文章
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1987年學術文章
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name
The propeptide region of clott ...... engineering of amino acid -4.
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type
label
The propeptide region of clott ...... engineering of amino acid -4.
@en
prefLabel
The propeptide region of clott ...... engineering of amino acid -4.
@en
P2860
P356
P1476
The propeptide region of clott ...... engineering of amino acid -4.
@en
P2093
Brownlee GG
P2860
P304
P356
10.1093/NAR/15.22.9505
P577
1987-11-01T00:00:00Z