about
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brainEpigenetic modifications in cancerThe cis -(5 R ,6 S )-Thymine Glycol Lesion Occupies the Wobble Position When Mismatched with Deoxyguanosine in DNABinding of the human nucleotide excision repair proteins XPA and XPC/HR23B to the 5R-thymine glycol lesion and structure of the cis-(5R,6S) thymine glycol epimer in the 5'-GTgG-3' sequence: destabilization of two base pairs at the lesion siteSubstrate specificity of human endonuclease III (hNTH1). Effect of human APE1 on hNTH1 activityEfficient formation of the tandem thymine glycol/8-oxo-7,8-dihydroguanine lesion in isolated DNA and the mutagenic and cytotoxic properties of the tandem lesions in Escherichia coli cells.5-methylcytosine in RNA: detection, enzymatic formation and biological functions.Totipotency in the mouse.Targeted deletion of mNth1 reveals a novel DNA repair enzyme activity.Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG-->TT tandem mutations at methylated CpG dinucleotides in nucleotide excision repair-deficient cells.Synthesis of stable-isotope enriched 5-methylpyrimidines and their use as probes of base reactivity in DNA.Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatinIs thymidine glycol containing DNA a substrate of E. coli DNA mismatch repair system?Quantification of oxidative single-base and intrastrand cross-link lesions in unmethylated and CpG-methylated DNA induced by Fenton-type reagents.Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair.NEIL1 binding to DNA containing 2'-fluorothymidine glycol stereoisomers and the effect of editingThe mammalian de novo DNA methyltransferases DNMT3A and DNMT3B are also DNA 5-hydroxymethylcytosine dehydroxymethylases.Synthesis and thermodynamic studies of oligodeoxyribonucleotides containing tandem lesions of thymidine glycol and 8-oxo-2'-deoxyguanosineTargeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA.In vitro replication and repair studies of tandem lesions containing neighboring thymidine glycol and 8-oxo-7,8-dihydro-2'-deoxyguanosineKinetics of deamination and Cu(II)/H2O2/Ascorbate-induced formation of 5-methylcytosine glycol at CpG sites in duplex DNA.Mutational spectra of human cancer.Occurrence, Biological Consequences, and Human Health Relevance of Oxidative Stress-Induced DNA Damage.Stimulation of N--glycoside transfer in deoxythymidine glycol: mechanism of the initial step in base excision repair.DNA glycosylases in the base excision repair of DNAReactions of 5-methylcytosine cation radicals in DNA and model systems: thermal deprotonation from the 5-methyl group vs. excited state deprotonation from sugar.Interconversion of the cis-5R,6S- and trans-5R,6R-thymine glycol lesions in duplex DNA.Quantum mechanics study and Monte Carlo simulation on the hydrolytic deamination of 5-methylcytosine glycol.Hydrolysis of the damaged deoxythymidine glycol nucleoside and comparison to canonical DNA.
P2860
Q22065852-C12CAA39-E2E1-47D1-8CBD-2045EB4A29A1Q22242610-3ACA4E0F-94FB-414A-B921-A32E7F103E67Q27657520-1B62FA3B-9BE0-46DE-98D9-732E481A0A07Q27658074-F6B58878-8A5B-4C31-BEEB-861B0784959FQ28202324-A8DD031B-BC1D-4F2E-8605-D537A9747CFDQ30492801-B4B084A9-0DDE-43E3-8998-D282BE752FF6Q33719364-D7124288-7CEB-4C31-BCB3-08330707A767Q33843609-981BCEBD-998E-49F9-908F-8B245C2DEB93Q34285514-37133C68-B453-4968-8C56-EF865858AFDEQ34291002-EDD64A0C-161A-413E-8C3B-F717A55C2E58Q34367213-035403F8-B773-4056-B564-96559A85EFB4Q35057331-86911DFF-B345-4B3A-A19F-64261AF7A6E0Q35227178-BF5BD3B4-6BA2-475D-8AFE-3B8C93115801Q35990410-C2E39361-77CD-43D1-B7F7-F988B2844115Q36079274-A93D7511-81F4-400B-88CF-FAF487E31C31Q36266557-1853F0DF-3343-436B-9598-5156BC4991DFQ36286073-2CC50BCB-6658-454D-A8D8-8A9C9633A8B9Q36871447-27B43532-B907-4FC9-8242-518CAE5D36B6Q36972337-99BEB7C8-6C5E-4A3B-BAFD-4142B4C32AFBQ37395678-40F48142-D09E-4B1D-92C2-188CB63A105DQ37406022-36D43FF9-A43F-4262-838A-AF9BCCE02153Q37421430-BB639A60-FE77-4889-9D4B-5BC77CFBCC2AQ38434331-3684F1A2-0816-414C-A5A7-D9F7A2F9140FQ39238812-2AA7859B-614E-4CAC-80AC-EC279D01A88DQ41532551-69720720-23E3-4447-A1D0-AB09F825D586Q41904882-B6021E5A-E786-4FA5-8DED-759A9F9F2E5BQ43176326-EDDA964F-D786-4AA9-852A-C3EA940DDB3CQ50525540-06B33B56-2F07-4764-8743-D42C2E54E98EQ54768076-582CF263-2D7C-4B30-B7B7-43228EAFA8C4
P2860
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Oxidative damage to 5-methylcytosine in DNA.
@en
type
label
Oxidative damage to 5-methylcytosine in DNA.
@en
prefLabel
Oxidative damage to 5-methylcytosine in DNA.
@en
P2860
P356
P1476
Oxidative damage to 5-methylcytosine in DNA
@en
P2093
P2860
P304
P356
10.1093/NAR/23.16.3239
P577
1995-08-01T00:00:00Z