Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate.
about
Characterization of SpPol4, a unique X-family DNA polymerase in Schizosaccharomyces pombe.Molecular Basis for DNA Double-Strand Break Annealing and Primer Extension by an NHEJ DNA PolymerasePolymerase mu is up-regulated during the T cell-dependent immune response and its deficiency alters developmental dynamics of spleen centroblastsMolecular characterization of spontaneous mesenchymal stem cell transformationDifferent mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversificationError-prone DNA repair activity during somatic hypermutation in shark B lymphocytesYeast pol4 promotes tel1-regulated chromosomal translocations.Modulation of Pleurodeles waltl DNA polymerase mu expression by extreme conditions encountered during spaceflight.Polμ deficiency increases resistance to oxidative damage and delays liver aging.Increased neuronal death and disturbed axonal growth in the Polμ-deficient mouse embryonic retina.A role for DNA polymerase mu in the emerging DJH rearrangements of the postgastrulation mouse embryo.Limited terminal transferase in human DNA polymerase mu defines the required balance between accuracy and efficiency in NHEJ.Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.Expression of Mycobacterium tuberculosis Ku and Ligase D in Escherichia coli results in RecA and RecB-independent DNA end-joining at regions of microhomology.A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis.DNA expansions generated by human Polμ on iterative sequences.Polμ tumor variants decrease the efficiency and accuracy of NHEJ.Analysis of the relationship between coexpression domains and chromatin 3D organization.Ribonucleotides and manganese ions improve non-homologous end joining by human Polμ.
P2860
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P2860
Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate.
description
2004 nî lūn-bûn
@nan
2004年の論文
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2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Overexpression of human DNA po ...... he somatic hypermutation rate.
@en
type
label
Overexpression of human DNA po ...... he somatic hypermutation rate.
@en
prefLabel
Overexpression of human DNA po ...... he somatic hypermutation rate.
@en
P2093
P2860
P356
P1476
Overexpression of human DNA po ...... he somatic hypermutation rate.
@en
P2093
Ana I Saez
Antonio Bernad
Daniel Lucas
Esther García-Palomero
Luis Blanco
Manuel A González
P2860
P304
P356
10.1093/NAR/GKH929
P577
2004-11-01T00:00:00Z