Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer.
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BRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implicationsEpigenetic alterations in RASSF1A in human aberrant crypt fociPromoter methylation of RASSF1A and DAPK and mutations of K-ras, p53, and EGFR in lung tumors from smokers and never-smokers.Aberrant gene promoter methylation associated with sporadic multiple colorectal cancerMixed lineage kinase 3 gene mutations in mismatch repair deficient gastrointestinal tumours.Role of RECK methylation in gastric cancer and its clinical significanceRASSF1A promoter hypermethylation is a strong biomarker of poor survival in patients with salivary adenoid cystic carcinoma in a Chinese population.Aberrant promoter methylation of RASSF1A gene may be correlated with colorectal carcinogenesis: a meta-analysis.Colorectal cancer: a model for epigenetic tumorigenesis.Genetic and epigenetic alterations of Ras signalling pathway in colorectal neoplasia: analysis based on tumour clinicopathological features.RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1AGene expression deregulation by KRAS G12D and G12V in a BRAF V600E context.Inhibition of nuclear factor-kappa B enhances the tumor growth of ovarian cancer cell line derived from a low-grade papillary serous carcinoma in p53-independent pathwayDetection of RASSF1A promoter hypermethylation in serum from gastric and colorectal adenocarcinoma patients.BRAF(V600E) efficient transformation and induction of microsatellite instability versus KRAS(G12V) induction of senescence markers in human colon cancer cells.Diminished expression of MGMT & RASSF1A genes in gastric cancer in ethnic population of KashmirColorectal cancer and RASSF family--a special emphasis on RASSF1A.Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells.Microsatellite instability in gallbladder carcinoma.β-catenin interaction with NHERF1 and RASSF1A methylation in metastatic colorectal cancer patientsMethylation status of the APC and RASSF1A promoter in cell-free circulating DNA and its prognostic role in patients with colorectal cancer.Loss of Rassf1a cooperates with Apc(Min) to accelerate intestinal tumourigenesis.Promoter hypermethylation of RASSF1A, MGMT, and HIC-1 genes in benign and malignant colorectal tumors.Mapping of genetic deletions on chromosome 3 in colorectal cancer: loss of 3p25-pter is associated with distant metastasis and poor survival.Hypermethylation of protocadherin γ subfamily A12 and solute carrier family 19 A 1 promoters contributes to the occurrence and metastasis of colorectal cancer.Promoter methylation of the RASSF1A gene may contribute to colorectal cancer susceptibility: a meta-analysis of cohort studiesKRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression
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P2860
Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Concomitant RASSF1A hypermethy ...... SI sporadic colorectal cancer.
@en
type
label
Concomitant RASSF1A hypermethy ...... SI sporadic colorectal cancer.
@en
prefLabel
Concomitant RASSF1A hypermethy ...... SI sporadic colorectal cancer.
@en
P2093
P2860
P50
P356
P1433
P1476
Concomitant RASSF1A hypermethy ...... SI sporadic colorectal cancer.
@en
P2093
Enric Domingo
Hiroyuki Yamamoto
Richard Hamelin
Robert M W Hofstra
Simo Schwartz
P2860
P2888
P304
P356
10.1038/SJ.ONC.1208906
P407
P577
2005-11-01T00:00:00Z
P5875
P6179
1001626065