Tyrosine phosphorylation regulates the proteolytic activation of protein kinase Cdelta in dopaminergic neuronal cells.
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Nutraceuticals in Parkinson's Diseaseα-Synuclein protects against manganese neurotoxic insult during the early stages of exposure in a dopaminergic cell model of Parkinson's diseaseVanadium induces dopaminergic neurotoxicity via protein kinase Cdelta dependent oxidative signaling mechanisms: relevance to etiopathogenesis of Parkinson's diseaseProtein kinase Cdelta-dependent and -independent signaling in genotoxic response to treatment of desferroxamine, a hypoxia-mimetic agentα-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activityProtein kinase D1 (PKD1) activation mediates a compensatory protective response during early stages of oxidative stress-induced neuronal degenerationCyanide-induced death of dopaminergic cells is mediated by uncoupling protein-2 up-regulation and reduced Bcl-2 expressionInteraction of cyanide and nitric oxide with cytochrome c oxidase: implications for acute cyanide toxicity.Inhibiting tyrosine phosphorylation of protein kinase Cδ (PKCδ) protects the salivary gland from radiation damageNovel cell death signaling pathways in neurotoxicity models of dopaminergic degeneration: relevance to oxidative stress and neuroinflammation in Parkinson's disease.Lipocalin-type prostaglandin D synthase protects against oxidative stress-induced neuronal cell death.PKC-δ mediates interferon-α-induced apoptosis through c-Jun NH₂-terminal kinase activation.Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCdelta proteolytic activation and mitochondrial translocation.Transcriptional regulation of pro-apoptotic protein kinase Cdelta: implications for oxidative stress-induced neuronal cell death.Multiple PKCdelta tyrosine residues are required for PKCdelta-dependent activation of involucrin expression--a key role of PKCdelta-Y311.Protein kinase D1 (PKD1) phosphorylation promotes dopaminergic neuronal survival during 6-OHDA-induced oxidative stress.Manganese nanoparticle activates mitochondrial dependent apoptotic signaling and autophagy in dopaminergic neuronal cellsDopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's diseaseFyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's DiseaseEnvironmental neurotoxic pesticide dieldrin activates a non receptor tyrosine kinase to promote PKCδ-mediated dopaminergic apoptosis in a dopaminergic neuronal cell model.Emerging neurotoxic mechanisms in environmental factors-induced neurodegeneration.Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammationPharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cellsN-Acetyl Cysteine Protects against Methamphetamine-Induced Dopaminergic Neurodegeneration via Modulation of Redox Status and Autophagy in Dopaminergic Cells.Isozyme-specific interaction of protein kinase Cδ with mitochondria dissected using live cell fluorescence imaging.Phosphorylation of protein kinase Cdelta on distinct tyrosine residues induces sustained activation of Erk1/2 via down-regulation of MKP-1: role in the apoptotic effect of etoposidePhorbol 12-myristate 13-acetate-dependent protein kinase C delta-Tyr311 phosphorylation in cardiomyocyte caveolae.Chronic low-dose oxidative stress induces caspase-3-dependent PKCdelta proteolytic activation and apoptosis in a cell culture model of dopaminergic neurodegeneration.Role of proteolytic activation of protein kinase Cδ in the pathogenesis of prion disease.Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease.Protein kinase Cδ and caspase-3 modulate TRAIL-induced apoptosis in breast tumor cells.Curcumin enhances paraquat-induced apoptosis of N27 mesencephalic cells via the generation of reactive oxygen species.Caspase-mediated protein kinase C-delta cleavage is necessary for apoptosis of vascular smooth muscle cellsAndrogens induce dopaminergic neurotoxicity via caspase-3-dependent activation of protein kinase Cdelta.PKCδ inhibition enhances tyrosine hydroxylase phosphorylation in mice after methamphetamine treatment.Tuning the signalling output of protein kinase C.Pharmacology of Src family kinases and therapeutic implications of their modulators.Protein kinase C delta mediated cytotoxicity of 6-Hydroxydopamine via sustained extracellular signal-regulated kinase 1/2 activation in PC12 cells.Current understanding of methamphetamine-associated dopaminergic neurodegeneration and psychotoxic behaviors.Roles of PKC isoforms in the induction of apoptosis elicited by aberrant Ras.
P2860
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P2860
Tyrosine phosphorylation regulates the proteolytic activation of protein kinase Cdelta in dopaminergic neuronal cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Tyrosine phosphorylation regul ...... n dopaminergic neuronal cells.
@en
type
label
Tyrosine phosphorylation regul ...... n dopaminergic neuronal cells.
@en
prefLabel
Tyrosine phosphorylation regul ...... n dopaminergic neuronal cells.
@en
P2093
P2860
P921
P356
P1476
Tyrosine phosphorylation regul ...... n dopaminergic neuronal cells.
@en
P2093
Anumantha G Kanthasamy
Arthi Kanthasamy
Christopher J Choi
Siddharth Kaul
Vellareddy Anantharam
Yongjie Yang
P2860
P304
28721-28730
P356
10.1074/JBC.M501092200
P407
P577
2005-06-16T00:00:00Z