Molecular determinants of glycine receptor alphabeta subunit sensitivities to Zn2+-mediated inhibition.
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Molecular basis for zinc potentiation at strychnine-sensitive glycine receptorsZinc-dependent modulation of α2- and α3-glycine receptor subunits by ethanol.Differentiated human midbrain-derived neural progenitor cells express excitatory strychnine-sensitive glycine receptors containing α2β subunitsEthanol effects on glycinergic transmission: From molecular pharmacology to behavior responsesMurine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation.Mutation of a zinc-binding residue in the glycine receptor α1 subunit changes ethanol sensitivity in vitro and alcohol consumption in vivoAllosteric modulation of glycine receptors.The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels.GABA and glycine as neurotransmitters: a brief history.Zinc enhances ethanol modulation of the alpha1 glycine receptor.Pulsed electron spin resonance resolves the coordination site of Cu²(+) ions in α1-glycine receptorZinc modulation of glycine receptorsFast synaptic inhibition in spinal sensory processing and pain control.The Free Zinc Concentration in the Synaptic Cleft of Artificial Glycinergic Synapses Rises to At least 1 μMNon-agonist-binding subunit interfaces confer distinct functional signatures to the alternate stoichiometries of the alpha4beta2 nicotinic receptor: an alpha4-alpha4 interface is required for Zn2+ potentiation.The GLRA1 missense mutation W170S associates lack of Zn2+ potentiation with human hyperekplexia.Synaptic neurotransmitter-gated receptorsStructure and Pharmacologic Modulation of Inhibitory Glycine Receptors.Allosteric modulation of the glycine receptor activated by agonists differing in efficacy.Mapping a molecular link between allosteric inhibition and activation of the glycine receptor.Zinc as a Neuromodulator in the Central Nervous System with a Focus on the Olfactory Bulb.The M4 transmembrane segment contributes to agonist efficacy differences between alpha1 and alpha3 glycine receptors.Zinc enhances the inhibitory effects of strychnine-sensitive glycine receptors in mouse hippocampal neurons.Probing the pharmacological properties of distinct subunit interfaces within heteromeric glycine receptors reveals a functional ββ agonist-binding site.Alterations in ethanol-induced accumbal transmission after acute and long-term zinc depletion.
P2860
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P2860
Molecular determinants of glycine receptor alphabeta subunit sensitivities to Zn2+-mediated inhibition.
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2005 nî lūn-bûn
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name
Molecular determinants of glyc ...... s to Zn2+-mediated inhibition.
@en
type
label
Molecular determinants of glyc ...... s to Zn2+-mediated inhibition.
@en
prefLabel
Molecular determinants of glyc ...... s to Zn2+-mediated inhibition.
@en
P2860
P1476
Molecular determinants of glyc ...... s to Zn2+-mediated inhibition.
@en
P2093
Marco Beato
Trevor G Smart
P2860
P304
P356
10.1113/JPHYSIOL.2005.088575
P407
P577
2005-05-19T00:00:00Z