Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes
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Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cellsIA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas.The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cellsRETRACTED: Alternative splicing produces high levels of noncoding isoforms of bHLH transcription factors during developmentRecapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cellsIdentification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional networkDevelopmental expression and cardiac transcriptional regulation of Myh7b, a third myosin heavy chain in the vertebrate heartPdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylationPdx1 and Ngn3 overexpression enhances pancreatic differentiation of mouse ES cell-derived endoderm populationDevelopment and differentiation of the intestinal epitheliumProendocrine genes coordinate the pancreatic islet differentiation program in vitroHuman pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregatesIn vitro culture of embryonic mouse intestinal epithelium: cell differentiation and introduction of reporter genes.Preservation of proliferating pancreatic progenitor cells by Delta-Notch signaling in the embryonic chicken pancreas.Beta cells within single human islets originate from multiple progenitors.Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axisNeurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas.Protein therapy using MafA fused to a polyarginine transduction domain attenuates glucose levels of streptozotocin‑induced diabetic mice.Regeneration of pancreatic islets in vivo by ultrasound-targeted gene therapy.Direct lineage conversions: unnatural but useful?Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming.Serotonin and GI Disorders: An Update on Clinical and Experimental Studies.Pluripotent cells (stem cells) and their determination and differentiation in early vertebrate embryogenesis.A CRM1-mediated nuclear export signal is essential for cytoplasmic localization of neurogenin 3 in neurons.Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas.Permanent Neonatal Diabetes and Enteric Anendocrinosis Associated With Biallelic Mutations in NEUROG3.OVO homologue-like 1 (Ovol1) transcription factor: a novel target of neurogenin-3 in rodent pancreas.Development and diseases of the pancreas.Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish.Sox9: a master regulator of the pancreatic program.The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice.G protein-coupled receptor signaling and sphingosine-1-phosphate play a phylogenetically conserved role in endocrine pancreas morphogenesisEmbryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression.Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells.Harnessing the gut to treat diabetes.Can diabetes be cured by therapeutic cloning?PDX1 regulation of FABP1 and novel target genes in human intestinal epithelial Caco-2 cellsThe molecular basis and prospects in pancreatic development.Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation.
P2860
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P2860
Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Key events of pancreas formati ...... of pancreatic regulatory genes
@en
type
label
Key events of pancreas formati ...... of pancreatic regulatory genes
@en
prefLabel
Key events of pancreas formati ...... of pancreatic regulatory genes
@en
P2860
P356
P1433
P1476
Key events of pancreas formati ...... of pancreatic regulatory genes
@en
P2093
Majithia AR
P2860
P304
P356
10.1101/GAD.846001
P577
2001-02-01T00:00:00Z