Dmp1 is haplo-insufficient for tumor suppression and modifies the frequencies of Arf and p53 mutations in Myc-induced lymphomas
about
No evidence for involvement of SDHD in neuroblastoma pathogenesisNovel Molecular Markers for Breast CancerAberrant Splicing of Estrogen Receptor, HER2, and CD44 Genes in Breast CancerInhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genesMMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancerInactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiencyGeneration and initial characterization of the prolactin-inducible protein (PIP) null mouse: accompanying global changes in gene expression in the submandibular glandThe Arf-inducing transcription factor Dmp1 encodes a transcriptional activator of amphiregulin, thrombospondin-1, JunB and Egr1Haploinsufficiency of Anx7 tumor suppressor gene and consequent genomic instability promotes tumorigenesis in the Anx7(+/-) mouseThe direct effect of focal adhesion kinase (FAK), dominant-negative FAK, FAK-CD and FAK siRNA on gene expression and human MCF-7 breast cancer cell tumorigenesis.Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor.Haploinsufficient tumor suppressor genes.Classical and Novel Prognostic Markers for Breast Cancer and their Clinical Significance.From General Aberrant Alternative Splicing in Cancers and Its Therapeutic Application to the Discovery of an Oncogenic DMTF1 Isoform.Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis.Reduction of Pten dose leads to neoplastic development in multiple organs of Pten (shRNA) miceCritical roles of DMP1 in human epidermal growth factor receptor 2/neu-Arf-p53 signaling and breast cancer development.A mouse model of human oral-esophageal cancer.Dmp1α inhibits HER2/neu-induced mammary tumorigenesis.Signal transduction involving the dmp1 transcription factor and its alteration in human cancerDMP1β, a splice isoform of the tumour suppressor DMP1 locus, induces proliferation and progression of breast cancerComparative pathogenesis of epsilonretroviruses.Regulation of murine hematopoietic stem cell quiescence by Dmtf1Hypergrowth mTORC1 signals translationally activate the ARF tumor suppressor checkpoint.MicroRNA-155 promotes bladder cancer growth by repressing the tumor suppressor DMTF1.Dmp1 and tumor suppression.Expression of Dmp1 in specific differentiated, nonproliferating cells and its regulation by E2FsTumor suppressor genetics.Human DMTF1β antagonizes DMTF1α regulation of the p14(ARF) tumor suppressor and promotes cellular proliferation.H2AX haploinsufficiency modifies genomic stability and tumor susceptibilityp53-Dependent and -independent functions of the Arf tumor suppressor.Cutaneous melanoma in genetically modified animals.Emerging roles of DMP1 in lung cancerHIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumorsPrognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer.Role of DMP1 and its future in lung cancer diagnostics.Scaffold Attachment Factor B1 (SAFB1) heterozygosity does not influence Wnt-1 or DMBA-induced tumorigenesisCooperation between Dmp1 loss and cyclin D1 overexpression in breast cancer.Aberrant splicing of the DMP1-ARF-MDM2-p53 pathway in cancerDicer1 functions as a haploinsufficient tumor suppressor.
P2860
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P2860
Dmp1 is haplo-insufficient for tumor suppression and modifies the frequencies of Arf and p53 mutations in Myc-induced lymphomas
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Dmp1 is haplo-insufficient for ...... tions in Myc-induced lymphomas
@en
type
label
Dmp1 is haplo-insufficient for ...... tions in Myc-induced lymphomas
@en
prefLabel
Dmp1 is haplo-insufficient for ...... tions in Myc-induced lymphomas
@en
P2093
P2860
P356
P1433
P1476
Dmp1 is haplo-insufficient for ...... tions in Myc-induced lymphomas
@en
P2093
P2860
P304
P356
10.1101/GAD.929901
P577
2001-11-01T00:00:00Z