Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast. - Wikidata - awgldk - TriplyDB

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast.

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast.

http://www.wikidata.org/entity/Q40430046

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The NEDD8 modification pathway in plants Cullin-RING ubiquitin ligases: global regulation and activation cycles A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8 The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73 A new ubiquitin ligase involved in p57KIP2 proteolysis regulates osteoblast cell differentiation The UBA domains of NUB1L are required for binding but not for accelerated degradation of the ubiquitin-like modifier FAT10 An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells.The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1 Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein Degradation Functional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteins The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p Conservation of the COP9/signalosome in budding yeast Posttranslational modifications of proteins in the pathobiology of medically relevant fungi Structural basis for the function of DCN-1 in protein Neddylation Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8’s E1 † ‡E2-binding surface on Uba3 β-grasp domain undergoes a conformational transition A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression.F-box protein Grr1 interacts with phosphorylated targets via the cationic surface of its leucine-rich repeat.The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34 DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1 Substrate-mediated regulation of cullin neddylation Inference of protein complex activities from chemical-genetic profile and its applications: predicting drug-target pathways The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation.Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases.Regulation of the G1 to S transition by the ubiquitin pathway.AXR1-ECR1-dependent conjugation of RUB1 to the Arabidopsis Cullin AtCUL1 is required for auxin response.Arabidopsis E2Fc functions in cell division and is degraded by the ubiquitin-SCF(AtSKP2) pathway in response to light.The essential functions of NEDD8 are mediated via distinct surface regions, and not by polyneddylation in Schizosaccharomyces pombe.Fission yeast F-box protein Pof3 is required for genome integrity and telomere function.Protein neddylation: beyond cullin-RING ligases.Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase C. elegans CAND-1 regulates cullin neddylation, cell proliferation and morphogenesis in specific tissues Cell type-dependent requirement for PIP box-regulated Cdt1 destruction during S phase.Neddylation dysfunction in Alzheimer's disease.De novo DNA methyltransferase DNMT3b interacts with NEDD8-modified proteins.Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy Local ubiquitin-proteasome-mediated proteolysis and long-term synaptic plasticity.Auxin perception--structural insights

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P2860

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast.

http://www.wikidata.org/entity/Q40430046

description

2000 nî lūn-bûn

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2000年の論文

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年學術文章

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2000年學術文章

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2000年學術文章

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name

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast.

@en

type

label

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast.

@en

prefLabel

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast.

@en

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P1433

The EMBO Journal

P1476

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast.

@en

P2093

A Toh-E

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F Osaka

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K Kominami

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K Tanaka

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M Saeki

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S Katayama

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Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

The amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons

A new NEDD8-ligating system for cullin-4A

Structure and functions of the 20S and 26S proteasomes

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha

The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2

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3475-3484

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10.1093/EMBOJ/19.13.3475

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13

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19

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12439435

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10880460

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313942

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