CD8+ cytotoxic T lymphocyte activation by soluble major histocompatibility complex-peptide dimers.
about
Activation of the Hedgehog signaling pathway in T-lineage cells inhibits TCR repertoire selection in the thymus and peripheral T-cell activationIdentifying Individual T Cell Receptors of Optimal Avidity for Tumor AntigensLinking form to function: Biophysical aspects of artificial antigen presenting cell designStructural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptorPhotocrosslinkable pMHC monomers stain T cells specifically and cause ligand-bound TCRs to be 'preferentially' transported to the cSMAC.How the immune system talks to itself: the varied role of synapsesEvidence that the density of self peptide-MHC ligands regulates T-cell receptor signaling.Physical and functional bivalency observed among TCR/CD3 complexes isolated from primary T cells.Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response.NK Cells Respond to Haptens by the Activation of Calcium Permeable Plasma Membrane Channels.A constant affinity threshold for T cell tolerance.A role for "self" in T-cell activationRecognition of self-peptide-MHC complexes by autoimmune T-cell receptors.Analysis, Isolation, and Activation of Antigen-Specific CD4(+) and CD8(+) T Cells by Soluble MHC-Peptide Complexes.Self-class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levelsDynamic organization of lymphocyte plasma membrane: lessons from advanced imaging methods.Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes.Dendritic cells enhance the antigen sensitivity of T cells.Mucopolysaccharide diseases: a complex interplay between neuroinflammation, microglial activation and adaptive immunity.MHC class I dimer formation by alteration of the cellular redox environment and induction of apoptosis.Increased mobility of major histocompatibility complex I-peptide complexes decreases the sensitivity of antigen recognitionTowards multivalent CD1d ligands: synthesis and biological activity of homodimeric α-galactosyl ceramide analogues.Initiation of TCR phosphorylation and signal transduction.Core-based lipid nanoparticles as a nanoplatform for delivery of near-infrared fluorescent imaging agents.Changing separating distances between immune receptors as a sensitive mechanism regulating T-cell activation.Protein-protein interaction investigated by steered molecular dynamics: the TCR-pMHC complex.Modulation of Naive CD8 T Cell Response Features by Ligand Density, Affinity, and Continued Signaling via Internalized TCRs.Nonstimulatory peptide-MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling.
P2860
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P2860
CD8+ cytotoxic T lymphocyte activation by soluble major histocompatibility complex-peptide dimers.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
CD8+ cytotoxic T lymphocyte ac ...... bility complex-peptide dimers.
@en
type
label
CD8+ cytotoxic T lymphocyte ac ...... bility complex-peptide dimers.
@en
prefLabel
CD8+ cytotoxic T lymphocyte ac ...... bility complex-peptide dimers.
@en
P2093
P2860
P356
P1476
CD8+ cytotoxic T lymphocyte ac ...... bility complex-peptide dimers.
@en
P2093
Bruno H Meyer
Horst Vogel
Immanuel F Luescher
Jean-Manuel Segura
Michael Bezard
Olivier Michielin
Philippe Guillaume
Silke Mark
P2860
P304
23820-23828
P356
10.1074/JBC.M500654200
P407
P577
2005-03-31T00:00:00Z