CD3 delta establishes a functional link between the T cell receptor and CD8
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Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptorThe multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cellsDifferential remodeling of a T-cell transcriptome following CD8- versus CD3-induced signaling.NSOM/QD-based direct visualization of CD3-induced and CD28-enhanced nanospatial coclustering of TCR and coreceptor in nanodomains in T cell activation.Altered function in CD8+ T cells following paramyxovirus infection of the respiratory tract.A transcription factor map as revealed by a genome-wide gene expression analysis of whole-blood mRNA transcriptome in multiple sclerosis.CD81 interacts with the T cell receptor to suppress signalingThe human CD8β M-4 isoform dominant in effector memory T cells has distinct cytoplasmic motifs that confer unique properties.CD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I.Spatial coordination of CD8 and TCR molecules controls antigen recognition by CD8+ T-cells.A constant affinity threshold for T cell tolerance.Modulation of MHC binding by lateral association of TCR and coreceptor.T-cell antigen receptor triggering and lipid rafts: a matter of space and time scales. Talking Point on the involvement of lipid rafts in T-cell activation.Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface.Analysis, Isolation, and Activation of Antigen-Specific CD4(+) and CD8(+) T Cells by Soluble MHC-Peptide Complexes.Tricks with tetramers: how to get the most from multimeric peptide-MHC.The T cell receptor's alpha-chain connecting peptide motif promotes close approximation of the CD8 coreceptor allowing efficient signal initiationVisualizing intermolecular interactions in T cells.Duality of the murine CD8 compartment.Solution structure of the CD3epsilondelta ectodomain and comparison with CD3epsilongamma as a basis for modeling T cell receptor topology and signaling.The CD4 and CD3δε Cytosolic Juxtamembrane Regions Are Proximal within a Compact TCR-CD3-pMHC-CD4 Macrocomplex.Loss of N-terminal charged residues of mouse CD3 epsilon chains generates isoforms modulating antigen T cell receptor-mediated signals and T cell receptor-CD3 interactions.Interactions between CD8alphabeta and the TCRalphabeta/CD3-receptor complex.CD8 kinetically promotes ligand binding to the T-cell antigen receptor.CD8+ cytotoxic T lymphocyte activation by soluble major histocompatibility complex-peptide dimers.Biochemical differences in the alphabeta T cell receptor.CD3 surface complex between CD8+ and CD4+ human mature T lymphocytes.The beta1 and beta3 integrins promote T cell receptor-mediated cytotoxic T lymphocyte activation.Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant regionInitiation of TCR phosphorylation and signal transduction.TCR Signaling Emerges from the Sum of Many PartsNonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse.Metallic gold slows disease progression, reduces cell death and induces astrogliosis while simultaneously increasing stem cell responses in an EAE rat model of multiple sclerosis.Glycosylation and the function of the T cell co-receptor CD8.Biochemical evidence for the presence of a single CD3delta and CD3gamma chain in the surface T cell receptor/CD3 complex.The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities.Feline degenerative joint disease: a genomic and proteomic approach
P2860
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P2860
CD3 delta establishes a functional link between the T cell receptor and CD8
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
CD3 delta establishes a functional link between the T cell receptor and CD8
@ast
CD3 delta establishes a functional link between the T cell receptor and CD8
@en
CD3 delta establishes a functional link between the T cell receptor and CD8
@nl
type
label
CD3 delta establishes a functional link between the T cell receptor and CD8
@ast
CD3 delta establishes a functional link between the T cell receptor and CD8
@en
CD3 delta establishes a functional link between the T cell receptor and CD8
@nl
prefLabel
CD3 delta establishes a functional link between the T cell receptor and CD8
@ast
CD3 delta establishes a functional link between the T cell receptor and CD8
@en
CD3 delta establishes a functional link between the T cell receptor and CD8
@nl
P2093
P2860
P356
P1476
CD3 delta establishes a functional link between the T cell receptor and CD8
@en
P2093
Dieter Naeher
Immanuel F Luescher
Laurence Goffin
Marie-Agnès Doucey
Olivier Michielin
Petra Baumgärtner
Philippe Guillaume
P2860
P304
P356
10.1074/JBC.M208119200
P407
P577
2003-01-31T00:00:00Z