Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1. - Wikidata - awgldk - TriplyDB

Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1.

Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1.

http://www.wikidata.org/entity/Q40444267

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The TRPM7 chanzyme is cleaved to release a chromatin-modifying kinase International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7 TRPM7 and its role in neurodegenerative diseases Crystal Structure of the -Kinase Domain of Dictyostelium Myosin Heavy Chain Kinase A The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity Differential regulation of transient receptor potential melastatin 6 and 7 cation channels by ANG II in vascular smooth muscle cells from spontaneously hypertensive rats TRP channels TRPM7 TRPM7 facilitates cholinergic vesicle fusion with the plasma membrane.Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosis.Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.Identification of Ser/Thr phosphorylation sites in the C2-domain of phospholipase C γ2 (PLCγ2) using TRPM7-kinase.Role of TRPM7 in Cancer: Potential as Molecular Biomarker and Therapeutic Target.Inactivation of TRPM7 kinase activity does not impair its channel function in mice.Methionine sulfoxide reductase B1 (MsrB1) recovers TRPM6 channel activity during oxidative stress TRPM6 kinase activity regulates TRPM7 trafficking and inhibits cellular growth under hypomagnesic conditions.The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k.The Mg2+ and Mg(2+)-nucleotide-regulated channel-kinase TRPM7.Transient receptor potential ion channel Trpm7 regulates exocrine pancreatic epithelial proliferation by Mg2+-sensitive Socs3a signaling in development and cancer.TRPM7 is required within zebrafish sensory neurons for the activation of touch-evoked escape behaviors.Insights into the regulation of eukaryotic elongation factor 2 kinase and the interplay between its domains.Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase Detailed examination of Mg2+ and pH sensitivity of human TRPM7 channels.Regulation of TRPM7 Function by IL-6 through the JAK2-STAT3 Signaling Pathway.TRPM7 and TRPM2-Candidate susceptibility genes for Western Pacific ALS and PD?Sensitivity of TRPM7 channels to Mg2+ characterized in cell-free patches of Jurkat T lymphocytes A critical role of TRPM channel-kinase for human magnesium transport.Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7 TRPM7 channel is regulated by magnesium nucleotides via its kinase domain.TRPM6 and TRPM7: A Mul-TRP-PLIK-cation of channel functions.Charge screening by internal pH and polyvalent cations as a mechanism for activation, inhibition, and rundown of TRPM7/MIC channels.Increase in serum Ca2+/Mg2+ ratio promotes proliferation of prostate cancer cells by activating TRPM7 channels.The long and arduous road to CRAC.TRPM7 is regulated by halides through its kinase domain Transient receptor potential melastatin 6 and 7 channels, magnesium transport, and vascular biology: implications in hypertension.TRP channels entering the structural era.TRPM7 and TRPM8 Ion Channels in Pancreatic Adenocarcinoma: Potential Roles as Cancer Biomarkers and Targets The functional network of ion channels in T lymphocytes

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P2860

Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1.

http://www.wikidata.org/entity/Q40444267

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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Channel function is dissociate ...... hosphorylation of TRPM7/ChaK1.

@en

type

label

Channel function is dissociate ...... hosphorylation of TRPM7/ChaK1.

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prefLabel

Channel function is dissociate ...... hosphorylation of TRPM7/ChaK1.

@en

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Journal of Biological Chemistry

P1476

Channel function is dissociate ...... hosphorylation of TRPM7/ChaK1.

@en

P2093

Brian T Chait

http://www.w3.org/2001/XMLSchema#string

Derek T McLachlin

http://www.w3.org/2001/XMLSchema#string

Fan-Yan Wei

http://www.w3.org/2001/XMLSchema#string

Hideki Matsui

http://www.w3.org/2001/XMLSchema#string

Hiroto Yamaguchi

http://www.w3.org/2001/XMLSchema#string

J Ashot Kozak

http://www.w3.org/2001/XMLSchema#string

Kazuhito Tomizawa

http://www.w3.org/2001/XMLSchema#string

Masayuki Matsushita

http://www.w3.org/2001/XMLSchema#string

Michael D Cahalan

http://www.w3.org/2001/XMLSchema#string

Yoshio Shimizu

http://www.w3.org/2001/XMLSchema#string

P2860

Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia

Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity

Green fluorescent protein as a marker for gene expression

Mapping the functional domains of elongation factor-2 kinase

TRP-PLIK, a bifunctional protein with kinase and ion channel activities

Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel

LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability

Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family

Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia

Elongation factor-2 kinase and its newly discovered relatives

P304

20793-20803

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scholarly article

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10.1074/JBC.M413671200

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P433

21

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280

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P577

2005-03-21T00:00:00Z

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P698

15781465

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