The kinetics of p53 activation versus cyclin E accumulation underlies the relationship between the spindle-assembly checkpoint and the postmitotic checkpoint.
about
Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 inductionSalt-inducible kinase 3 is a novel mitotic regulator and a target for enhancing antimitotic therapeutic-mediated cell death.p53 suppresses structural chromosome instability after mitotic arrest in human cells.Novel functions of the phosphatase SHP2 in the DNA replication and damage checkpoints.The CDK1 inhibitory kinase MYT1 in DNA damage checkpoint recovery.p53 deficiency enhances mitotic arrest and slippage induced by pharmacological inhibition of Aurora kinases.The requirement of p53 for maintaining chromosomal stability during tetraploidization.Cyclin A2-cyclin-dependent kinase 2 cooperates with the PLK1-SCFbeta-TrCP1-EMI1-anaphase-promoting complex/cyclosome axis to promote genome reduplication in the absence of mitosisDovitinib induces mitotic defects and activates the G2 DNA damage checkpoint.Fragile histidine triad (FHIT) gene and its association with p53 protein expression in the progression of gall bladder cancer.
P2860
Q30505355-28D38C51-DCA9-4036-82C1-74B1B0B1A858Q30577179-E0AF1CA2-B97C-4ED9-9D01-B15172C8C0FDQ33766312-3720B380-57B7-4595-821C-84E88D7140ABQ34493945-A3725A2E-F724-4883-A09C-C5F16C1D057EQ38320058-8D32DF0D-7EE2-42FC-8EC2-F53AC0116F52Q39108757-16A962AE-B5D0-4C49-9F3D-458DA205AD15Q40047194-BB7BCB83-72D4-4217-B2C3-E593E84470E0Q41868466-9458D61F-C2B7-4E5D-8298-CFA75CFCF5E7Q41923223-22BE92B0-010F-49E8-A068-826F7C245965Q46006357-24F93E43-5418-4FA0-BFC5-AAC5722F622E
P2860
The kinetics of p53 activation versus cyclin E accumulation underlies the relationship between the spindle-assembly checkpoint and the postmitotic checkpoint.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
The kinetics of p53 activation ...... nd the postmitotic checkpoint.
@en
type
label
The kinetics of p53 activation ...... nd the postmitotic checkpoint.
@en
prefLabel
The kinetics of p53 activation ...... nd the postmitotic checkpoint.
@en
P2093
P2860
P356
P1476
The kinetics of p53 activation ...... nd the postmitotic checkpoint.
@en
P2093
Kin Fan On
Pok Man Hau
Randy Y C Poon
Wan Mui Chan
Winnie Wong
Ying Wai Chan
P2860
P304
15716-15723
P356
10.1074/JBC.M800629200
P407
P577
2008-04-09T00:00:00Z