Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu-overexpressing breast cancer cells. - Wikidata - awgldk - TriplyDB

Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu-overexpressing breast cancer cells.

Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu-overexpressing breast cancer cells.

http://www.wikidata.org/entity/Q40456753

about

LncRNA HOTAIR: A master regulator of chromatin dynamics and cancer MicroRNAs as potential target in human bone and soft tissue sarcoma therapeutics Semaphorin 4D signaling requires the recruitment of phospholipase C gamma into the plexin-B1 receptor complex.Targeting cyclin B1 inhibits proliferation and sensitizes breast cancer cells to taxol.Validation of the Cancer BioChip System as a 3D siRNA screening tool for breast cancer targets Gene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodies Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer.FOXO1A is a target for HER2-overexpressing breast tumors.The role of HER2 in cancer therapy and targeted drug delivery Non-viral nanocarriers for siRNA delivery in breast cancer.Plasmid DNA delivery into MDA-MB-453 cells mediated by recombinant Her-NLS fusion protein.The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis Targeting the function of the HER2 oncogene in human cancer therapeutics.Critical roles of DMP1 in human epidermal growth factor receptor 2/neu-Arf-p53 signaling and breast cancer development.HER2-affitoxin: a potent therapeutic agent for the treatment of HER2-overexpressing tumors.Downregulation of human epidermal growth factor receptor 2 by short hairpin RNA increases chemosensitivity of human ovarian cancer cells Molecular profiling of individual tumor cells by hyperspectral microscopic imaging Induction of acquired resistance to antiestrogen by reversible mitochondrial DNA depletion in breast cancer cell line.Effects of ectopic HER-2/neu gene expression on the COX-2/PGE2/P450arom signaling pathway in endometrial carcinoma cells: HER-2/neu gene expression in endometrial carcinoma cells A human IgG-like bispecific antibody co-targeting epidermal growth factor receptor and the vascular endothelial growth factor receptor 2 for enhanced antitumor activity Allele-specific silencing of mutant p53 attenuates dominant-negative and gain-of-function activities.Therapeutic siRNA for drug-resistant HER2-positive breast cancer.Engineering a single ubiquitin ligase for the selective degradation of all activated ErbB receptor tyrosine kinases.Roles of competing endogenous RNAs in gastric cancer.Rapamycin-loaded Immunoliposomes Functionalized with Trastuzumab: A Strategy to Enhance Cytotoxicity to HER2-positive Breast Cancer Cells.Oligonucleotide-based theranostic nanoparticles in cancer therapy.Perspectives of HER2-targeting in gastric and esophageal cancer.Inhibition of ErbB-2 induces TFF3 downregulation in breast cancer cell lines.MMP-9 increases HER2/neu expression and alters apoptosis levels in human mammary epithelial cells (HMEC).Growth hormone receptor (GHR) RNAi decreases proliferation and enhances apoptosis in CMT-U27 canine mammary carcinoma cell line.Silencing oncogene expression in cervical cancer stem-like cells inhibits their cell growth and self-renewal ability.High expression of ErbB2 contributes to cholangiocarcinoma cell invasion and proliferation through AKT/p70S6K RNAi-mediated downregulation of uPAR synergizes with targeting of HER2 through the ERK pathway in breast cancer cells.ErbB-2 and met reciprocally regulate cellular signaling via plexin-B1.Chemically modified short interfering hybrids (siHYBRIDS): nanoimmunoliposome delivery in vitro and in vivo for RNAi of HER-2.Potentially functional variants in lncRNAs are associated with breast cancer risk in a Chinese population.HER2 induces cell proliferation and invasion of non-small-cell lung cancer by upregulating COX-2 expression via MEK/ERK signaling pathway.Down-regulation of C35 decreased the cell viability and migration of breast ductal carcinoma cells.Oncogene Knockdown via Active Loading of Small RNAs into Extracellular Vesicles by Sonication.Quantum dot-amphipol nanocomplex for intracellular delivery and real-time imaging of siRNA.

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P2860

Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu-overexpressing breast cancer cells.

http://www.wikidata.org/entity/Q40456753

description

2004 nî lūn-bûn

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2004年论文

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2004年论文

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2004年论文

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name

Silencing of the HER2/neu gene ...... xpressing breast cancer cells.

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type

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Silencing of the HER2/neu gene ...... xpressing breast cancer cells.

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Silencing of the HER2/neu gene ...... xpressing breast cancer cells.

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Silencing of the HER2/neu gene ...... xpressing breast cancer cells.

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P2093

Andrea Krämer

http://www.w3.org/2001/XMLSchema#string

Brigitte Zimmer

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Juping Yuan

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Klaus Strebhardt

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Manfred Kaufmann

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Timo Faltus

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P2860

Cell-cell adhesion mediated by binding of membrane-anchored ligand LERK-2 to the EPH-related receptor human embryonal kinase 2 promotes tyrosine kinase activity

The polo-like protein kinases Fnk and Snk associate with a Ca(2+)- and integrin-binding protein and are regulated dynamically with synaptic plasticity

Humanization of an anti-p185HER2 antibody for human cancer therapy

Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

RNA interference

Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

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6

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6

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15720805

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1531682

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