Block of Thalamic T-Type Ca(2+) Channels by Ethosuximide Is Not the Whole Story.
about
Molecular targets for antiepileptic drug developmentUsing C. elegans to discover therapeutic compounds for ageing-associated neurodegenerative diseasesHomeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potentialThe anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespanEthosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expressionChildhood absence epilepsy: genes, channels, neurons and networks.Early treatment suppresses the development of spike-wave epilepsy in a rat modelEthosuximide reduces electrographical and behavioral correlates of alcohol withdrawal seizure in DBA/2J mice.Towards the discovery of novel T-type calcium channel blockers.Induction of neuronal differentiation of rat muscle-derived stem cells in vitro using basic fibroblast growth factor and ethosuximide.Effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline on the protective action of various antiepileptic drugs in the maximal electroshock-induced seizure model: a type II isobolographic analysis.Targeting BK (big potassium) channels in epilepsy.The design and discovery of T-type calcium channel inhibitors for the treatment of central nervous system disorders.Low threshold T-type calcium channels as targets for novel epilepsy treatments.Are big potassium-type Ca(2+)-activated potassium channels a viable target for the treatment of epilepsy?The Role of Calcium Channels in Epilepsy.Potassium Channels in Epilepsy.Ethosuximide reduces ethanol withdrawal-mediated disruptions in sleep-related EEG patterns.Selective T-type calcium channel block in thalamic neurons reveals channel redundancy and physiological impact of I(T)windowActions of U-92032, a T-type Ca2+ channel antagonist, support a functional linkage between I(T) and slow intrathalamic rhythms.T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures.Contribution of intrinsic neuronal factors in the generation of cortically driven electrographic seizures.Photic-induced sensitization: acquisition of an augmenting spike-wave response in the adult rat through repeated strobe exposure.Synaptic Changes in AMPA Receptor Subunit Expression in Cortical Parvalbumin Interneurons in the Stargazer Model of Absence Epilepsy.The α2δ Subunit and Absence Epilepsy: Beyond Calcium Channels?Flow- and voltage-dependent blocking effect of ethosuximide on the inward rectifier K⁺ (Kir2.1) channel.Integrative properties and transfer function of cortical neurons initiating absence seizures in a rat genetic model.Effect of intracranial administration of ethosuximide in rats with spontaneous or pentylenetetrazol-induced spike-wave discharges.A Caenorhabditis elegans assay of seizure-like activity optimised for identifying antiepileptic drugs and their mechanisms of actionAntiepileptic Drugs Elevate Astrocytic Kir4.1 Expression in the Rat Limbic Region
P2860
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P2860
Block of Thalamic T-Type Ca(2+) Channels by Ethosuximide Is Not the Whole Story.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Block of Thalamic T-Type Ca(2+) Channels by Ethosuximide Is Not the Whole Story.
@en
type
label
Block of Thalamic T-Type Ca(2+) Channels by Ethosuximide Is Not the Whole Story.
@en
prefLabel
Block of Thalamic T-Type Ca(2+) Channels by Ethosuximide Is Not the Whole Story.
@en
P2860
P1433
P1476
Block of Thalamic T-Type Ca(2+) Channels by Ethosuximide Is Not the Whole Story
@en
P2093
Nathalie Leresche
Vincenzo Crunelli
P2860
P356
10.1046/J.1535-7597.2002.00024.X
P407
P577
2002-03-01T00:00:00Z